[2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone

Base Information

• Chemical Name: [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone
• CAS No.: 77832-44-1
• Molecular Formula: C₂₁H₁₂Br₃NO₂
• Molecular Weight: 550.044

Synonyms:[2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone

Chemical Property of [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

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Technology Process of [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone

There total 1 articles about [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

3,5-dibromo-4-hydroxy-benzoyl chloride (77823-55-3) + 2-(3-bromophenyl)indolizine (80488-98-8) → [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone (77832-44-1)

Guidance literature:

In 1,2-dichloro-ethane; for 40h; Ambient temperature;

Reference yield: 46.9%

1-chloro-3-(dipropylamino)propane (39743-36-7) + [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone (77832-44-1) → [2-(3-Bromo-phenyl)-indolizin-3-yl]-[3,5-dibromo-4-(3-dipropylamino-propoxy)-phenyl]-methanone; compound with oxalic acid (79282-98-7)

Guidance literature:

With potassium carbonate; In acetone; for 20h; Heating;

Reference yield: 39.9%

dibutyl-(3-chloro-propyl)-amine (36421-15-5) + [2-(3-Bromo-phenyl)-indolizin-3-yl]-(3,5-dibromo-4-hydroxy-phenyl)-methanone (77832-44-1) → [2-(3-Bromo-phenyl)-indolizin-3-yl]-[3,5-dibromo-4-(3-dibutylamino-propoxy)-phenyl]-methanone; compound with (E)-but-2-enedioic acid (79283-00-4)

Guidance literature:

With potassium carbonate; In acetone; for 20h; Heating;

upstream raw materials:

3,5-dibromo-4-hydroxy-benzoyl chloride

2-(3-bromophenyl)indolizine

Downstream raw materials:

[2-(3-Bromo-phenyl)-indolizin-3-yl]-[3,5-dibromo-4-(3-dibutylamino-propoxy)-phenyl]-methanone; compound with (E)-but-2-enedioic acid

[2-(3-Bromo-phenyl)-indolizin-3-yl]-[3,5-dibromo-4-(3-dipropylamino-propoxy)-phenyl]-methanone; compound with oxalic acid

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