(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Base Information

Chemical Name:(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione
CAS No.:238421-61-9
Molecular Formula:C₁₈H₂₂O₅
Molecular Weight:318.37
Hs Code.:

Synonyms:(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Suppliers and Price of (3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

There total 5 articles about (3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 78-94-4,25038-87-3
methyl vinyl ketone

: 238421-40-4
(5S)-4-hydroxy-3-(4-methoxyphenyl)-5-(2-propyl)-2(5H)-furanone

: 238421-61-9
(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

: (3S,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Guidance literature:: With triethylamine; In tetrahydrofuran; at 30 ℃; for 24h;

Reference yield:

: 17407-55-5
(S)-2-Hydroxy-3-methylbutanoic acid

: 238421-61-9
(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Guidance literature:: Multi-step reaction with 5 steps

1: 84 percent / conc. H₂SO₄ / 3.5 h / Heating

2: 79 percent / Et₃N / diethyl ether / 18 h / 20 °C

3: 92 percent / NBS; 2,2'-azobisbutyrinitrile / CCl₄ / 20 h / Heating

4: 43 percent / Mg; I₂ / tetrahydrofuran / 2 h / 20 °C

5: 90 percent / Et₃N / tetrahydrofuran / 24 h / 30 °C

With N-Bromosuccinimide; sulfuric acid; 2,2-azobisbutyronitrile; iodine; magnesium; triethylamine; In tetrahydrofuran; tetrachloromethane; diethyl ether; 1: Esterification / 2: Acylation / 3: Bromination / 4: Cyclization / 5: Addition;

Reference yield:

: 24347-63-5
methyl (S)-2-hydroxy-3-methylbutanoate

: 238421-61-9
(3R,5S)-3-(4-methoxyphenyl)-3-(3-oxobutyl)-5-(2-propyl)-2,4(3H,5H)-furadione

Guidance literature:: Multi-step reaction with 4 steps

1: 79 percent / Et₃N / diethyl ether / 18 h / 20 °C

2: 92 percent / NBS; 2,2'-azobisbutyrinitrile / CCl₄ / 20 h / Heating

3: 43 percent / Mg; I₂ / tetrahydrofuran / 2 h / 20 °C

4: 90 percent / Et₃N / tetrahydrofuran / 24 h / 30 °C

With N-Bromosuccinimide; 2,2-azobisbutyronitrile; iodine; magnesium; triethylamine; In tetrahydrofuran; tetrachloromethane; diethyl ether; 1: Acylation / 2: Bromination / 3: Cyclization / 4: Addition;