2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide

Base Information

• Chemical Name: 2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide
• CAS No.: 714570-38-4
• Molecular Formula: C₂₉H₂₄N₄O₄S
• Molecular Weight: 527.534

Synonyms:2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide

Chemical Property of 2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide

Chemical Property:

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Technology Process of 2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide

There total 1 articles about 2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(2R)-3-Oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide (714567-80-3) + [35S]2-naphthalenesulfonyl chloride (714570-29-3) → 2-[(2R)-1-(2-naphthyl[35S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide (714570-38-4)

Guidance literature:

With pyridine; 2,6-di-tert-butyl-pyridine; at 20 ℃;

Reference yield:

2-[(2R)-1-(2-naphthyl[35S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide (714570-38-4) + ethylenediamine (107-15-3,85404-18-8) → 2-[(2R)-1-(2-naphthyl[35S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-{2-[4-(4,5-dihydro-1H-imidazol-yl)phenyl]ethyl}acetamide (808770-58-3)

Guidance literature:

2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide; With hydrogenchloride; ethanol; at 20 ℃;

ethylenediamine; at 20 ℃; for 16h;

upstream raw materials:

2-[(2R)-3-Oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-[2-(4-cyanophenyl)ethyl]acetamide

[35S]2-naphthalenesulfonyl chloride

Downstream raw materials:

2-[(2R)-1-(2-naphthyl[³⁵S]sulfonyl)-3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl]-N-{2-[4-(4,5-dihydro-1H-imidazol-yl)phenyl]ethyl}acetamide

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