3-carboxymethylriboflavin

Base Information

• Chemical Name: 3-carboxymethylriboflavin
• CAS No.: 28714-80-9
• Molecular Formula: C₁₉H₂₂N₄O₈
• Molecular Weight: 434.406
• Mol file: 28714-80-9.mol

Synonyms:Benzo[g]pteridine-3(2H)-aceticacid,4,10-dihydro-7,8-dimethyl-2,4-dioxo-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-(8CI); 3-Carboxymethylriboflavin; N(3)-Carboxymethylriboflavin

Chemical Property of 3-carboxymethylriboflavin

Chemical Property:

• Vapor Pressure: 1.08E-25mmHg at 25°C
• Boiling Point: 781.2°Cat760mmHg
• Flash Point: 426.2°C
• PSA: 188.00000
• Density: 1.66g/cm³
• LogP: -2.11720

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-carboxymethylriboflavin

There total 3 articles about 3-carboxymethylriboflavin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tetra-O-acetyl riboflavin (752-13-6) → 3-carboxymethylriboflavin (28714-80-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / potassium carbonate / dimethylformamide / 20 h / 20 °C

2: aq. HCl / 2 h / Heating

With hydrogenchloride; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/ac034876a

Reference yield:

riboflavin (83-88-5,42880-33-1) → 3-carboxymethylriboflavin (28714-80-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / perchloric acid / acetic acid / 0.5 h / 40 °C

2: 73 percent / potassium carbonate / dimethylformamide / 20 h / 20 °C

3: aq. HCl / 2 h / Heating

With hydrogenchloride; perchloric acid; potassium carbonate; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/ac034876a

Reference yield:

[7,8-dimethyl-2,4-dioxo-10-(2,3,4,5-tetraacetoxy-pentyl)-4,10-dihydro-2H-benzo[g]pteridin-3-yl]-acetic acid ethyl ester (642988-86-1) → 3-carboxymethylriboflavin (28714-80-9)

Guidance literature:

With hydrogenchloride; for 2h; Heating;

DOI:10.1021/ac034876a

upstream raw materials:

[7,8-dimethyl-2,4-dioxo-10-(2,3,4,5-tetraacetoxy-pentyl)-4,10-dihydro-2H-benzo[g]pteridin-3-yl]-acetic acid ethyl ester

tetra-O-acetyl riboflavin

riboflavin