N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide

Base Information

• Chemical Name: N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide
• CAS No.: 1426399-72-5
• Molecular Formula: C₆₉H₇₁F₄N₅O₉
• Molecular Weight: 1190.34
• Mol file: 1426399-72-5.mol

Synonyms:N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide

Chemical Property of N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide

There total 12 articles about N¹-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N³,N⁵-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

N1-(4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)-N1-methylpropane-1,3-diamine (1426399-76-9) + 3,5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propylcarbamoyl)benzoic acid (1426399-78-1) → N1-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N3,N5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide (1426399-72-5)

Guidance literature:

N¹-(4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)-N¹-methylpropane-1,3-diamine; 3,5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propylcarbamoyl)benzoic acid; With benzotriazol-1-ol; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 120h; Inert atmosphere;

DOI:10.1016/j.tet.2013.01.075

Reference yield:

α,α’-dibromo-m-tetrafluoroxylene (776-40-9) → N1-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N3,N5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide (1426399-72-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 4 h / 160 °C

2.1: potassium tert-butylate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.2: 2 h / 0 °C / Inert atmosphere

3.1: potassium tert-butylate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

3.2: 3 h / 5 °C

4.1: hydrazine hydrate / ethanol / Reflux

5.1: benzotriazol-1-ol / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

5.2: 120 h / 20 °C / Inert atmosphere

With potassium tert-butylate; benzotriazol-1-ol; hydrazine hydrate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; 2.1: |Horner-Wadsworth-Emmons Olefination / 2.2: |Horner-Wadsworth-Emmons Olefination / 3.2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1016/j.tet.2013.01.075

Reference yield:

[4-((diethoxyphosphoryl)methyl)-2,3,5,6-tetrafluorobenzyl]phosphonic acid diethyl ester (288627-04-3) → N1-(3-((4-(4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorostyryl)phenyl)(methyl)amino)propyl)-N3,N5-bis(3-(4-methyl-2-oxo-2H-chromen-7-yloxy)propyl)benzene-1,3,5-tricarboxamide (1426399-72-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium tert-butylate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

1.2: 2 h / 0 °C / Inert atmosphere

2.1: potassium tert-butylate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.2: 3 h / 5 °C

3.1: hydrazine hydrate / ethanol / Reflux

4.1: benzotriazol-1-ol / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

4.2: 120 h / 20 °C / Inert atmosphere

With potassium tert-butylate; benzotriazol-1-ol; hydrazine hydrate; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; 1.1: |Horner-Wadsworth-Emmons Olefination / 1.2: |Horner-Wadsworth-Emmons Olefination / 2.2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1016/j.tet.2013.01.075

upstream raw materials:

α,α’-dibromo-m-tetrafluoroxylene

[4-((diethoxyphosphoryl)methyl)-2,3,5,6-tetrafluorobenzyl]phosphonic acid diethyl ester

(E)-diethyl 4-(4-(dibutylamino)styryl)-2,3,5,6-tetrafluorobenzylphosphonate

N-methylaniline

Refernces