3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate

Base Information

• Chemical Name: 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate
• CAS No.: 956582-18-6
• Molecular Formula: C₂₂H₂₆N₂O₂S
• Molecular Weight: 382.527
• Mol file: 956582-18-6.mol

Synonyms:3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate

Chemical Property of 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate

There total 3 articles about 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

6-tert-butyl-3-bromomethyl-2,4-dimethylphenyl acetate (956582-17-5) + Benzimidazol-2-thiol (134469-07-1) → 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate (956582-18-6)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 2.5h;

DOI:10.1134/S1070428006110091

Reference yield:

3-(bromomethyl)-6-tert-butyl-2,4-dimethylphenol (93982-04-8) → 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate (956582-18-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / clay kaolin K₁₀ / CH₂Cl₂ / 4 h / Heating

2: 92 percent / sodium methylate / methanol / 2.5 h / 20 °C

With clay kaolin K₁₀; sodium methylate; In methanol; dichloromethane;

DOI:10.1134/S1070428006110091

Reference yield:

2,4-dimethyl-6-tert-butylphenol (1879-09-0) → 3-{(1H-benzo[d]imidazol-2-ylsulfanyl)methyl}-6-tert-butyl-2,4-dimethyl-phenyl acetate (956582-18-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 68 percent / HBr

2: 100 percent / clay kaolin K₁₀ / CH₂Cl₂ / 4 h / Heating

3: 92 percent / sodium methylate / methanol / 2.5 h / 20 °C

With clay kaolin K₁₀; hydrogen bromide; sodium methylate; In methanol; dichloromethane;

DOI:10.1134/S1070428006110091

upstream raw materials:

6-tert-butyl-3-bromomethyl-2,4-dimethylphenyl acetate

Benzimidazol-2-thiol

3-(bromomethyl)-6-tert-butyl-2,4-dimethylphenol

2,4-dimethyl-6-tert-butylphenol