(R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde

Base Information

• Chemical Name: (R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde
• CAS No.: 1393802-63-5
• Molecular Formula: C₁₇H₂₆O₄Si
• Molecular Weight: 322.477
• Mol file: 1393802-63-5.mol

Synonyms:(R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde

Chemical Property of (R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde

There total 1 articles about (R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-tert-butyldimethylsilyloxy-2-methylpropanal (104701-87-3,115648-41-4,97826-89-6,91751-25-6) + dibenzoyl peroxide (94-36-0) → 2-methylpropenal (78-85-3,25120-30-3) + (R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde (1393802-63-5) + (S)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde

Guidance literature:

With 9-epi-9-amino-9-deoxyquinine; (S)-3,3'-bis(2,4,6-tri-iso-propylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; 2,6-di-tert-butyl-4-methyl-phenol; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tet.2012.06.043

Reference yield:

(R)-2-benzoyloxy-3-((tert-butyldimethylsilyl)oxy)-2-methyl-propionaldehyde (1393802-63-5) → (S)-3-((tert-butyldimethylsilyl)oxy)-2-hydroxy-2-methyl-propyl benzoate (1393802-95-3)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2012.06.043

upstream raw materials:

3-tert-butyldimethylsilyloxy-2-methylpropanal

dibenzoyl peroxide

Downstream raw materials:

(S)-3-((tert-butyldimethylsilyl)oxy)-2-hydroxy-2-methyl-propyl benzoate