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Product FOB Price Min.Order Supply Ability Supplier
Benzoyl peroxide-Low Price High Quality
Cas No: 94-36-0
No Data 1 Metric Ton 5 Metric Ton/Day Nantong Leadchem Industry Co.,Ltd Contact Supplier
benzoylbenzenecarboperoxoate 94-36-0
Cas No: 94-36-0
No Data No Data No Data Hunan Russell Chemicals Technology Co.,Ltd Contact Supplier
China Diluted Benzoyl peroxide, 98%, wetted with ca. 25% H2O
Cas No: 94-36-0
No Data 1 Metric Ton Metric Ton/Day Weifang Arylchem Chemical Co., LTD Contact Supplier
Benzoyl peroxide
Cas No: 94-36-0
No Data No Data No Data Pure Chemistry Scientific Inc. Contact Supplier

94-36-0 Usage

Uses

vitamin B complex

General Description

White, odorless powder, moderately toxic.

Uses

Source of free radicals for industrial processes. Oxidizing agent in bleaching oils, flour, etc.; catalyst in the plastics industry; initiator in polymerization.

Mode of action

Benzoyl peroxide is lipophilic that can penetrate the stratum corneum and enter the pilosebaceous follicle. It is rapidly broken down to benzoic acid and hydrogen peroxide and generates free radicals that oxidise proteins in bacterial cell membranes, exerting a bactericidal action. In addition, it has shown that benzoyl peroxide can reduce the free fatty acid content of sebum, which provides a useful marker for bacterial activity. Benzoyl peroxide has an anti-inflammatory action and vitro studies suggest that this action arises from its ability to kill polymorphonuclear leukocytes (PMN cells) in the pilosebaceous follicles and so prevent their release of reactive oxygen species such as peroxides which enhance tissue inflammation. Involving equation about this process:
C6H5C(O)O-OC(O)C6H5 + H2O 2 C6H5COOH + ½ O2
Moreover, due to its irritant effect, benzoyl peroxide increases turnover rate of epithelial cells, thereby peeling the skin and promoting the resolution of comedones.

Side effects as Acne Treatment

Skin reactions such as peeling, itching, irritation, and reddened skin may occur, especially at the start of treatment. A very serious allergic reaction to this drug is rare. This medicine may be harmful if swallowed.

Uses

Benzoyl Peroxide is a widely used organic compound of the peroxide family. Benzoyl Peroxide is often used in acne treatments , bleaching and polymerizing polyester and many other uses.

Benzoyl peroxide and Pregnancy

There are no studies looking at women who use topical benzoyl peroxide during pregnancy. When benzoyl peroxide is applied topically, only 5% is absorbed through the skin, and then it is completely metabolized to benzoic acid within the skin and excreted unchanged in the urine. It is not likely to increase risk for birth defects or cause problems for the baby. However, systemic effects on a pregnant woman and her child would not be expected and therefore use of this product during pregnancy would not be of concern.

Brand name

Acne-Aid Cream (Stiefel); Benoxyl (Stiefel); Benzac (Galderma); Benzac W (Galderma); Brevoxyl (Stiefel); Clear By Design (SmithKline Beecham); Dry and Clear (Whitehall-Robins); Epi-Clear (Bristol-Myers Squibb); Fostex BPO Bar, Gel, and Wash (Bristol-Myers Products); Loroxide (Dermik); PanOxyl (Stiefel); Persa-Gel (Ortho Pharmaceutical); Vanoxide (Dermik).

References

https://medlineplus.gov/druginfo/meds/a601026.html
https://pubchem.ncbi.nlm.nih.gov/compound/benzoyl_peroxide#section=Drug-and-Medication-Information
http://www.chm.bris.ac.uk/motm/benzoyl-peroxide/benzoylh.htm
https://www.webmd.com/drugs/2/drug-1344/benzoyl-peroxide-topical/details
https://pubchem.ncbi.nlm.nih.gov/compound/benzoyl_peroxide#section=Top
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3114665/
https://mothertobaby.org/fact-sheets/topical-acne-treatments-pregnancy/pdf/

Air & Water Reactions

Insoluble in water.

Other Uses


Benzoyl peroxide is used as a bleaching agent for certain foods, an oxidizing agent, a polymerizing initiator in the manufacture of plastics, a curing agent for silicone rubber, and an ingredient in various industrial processes.
Benzoyl peroxide, like most peroxides, is a powerful bleaching agent. It has a long history of use in the food industry as a bleaching agent added for flour, whey, and milk for cheese making. Contact with fabrics or hair can cause permanent color dampening almost immediately. Even secondary contact can cause bleaching.
Benzoyl peroxide is widely used as a catalyst in the polymerisation of molecules like styrene (phenylethene) to form polystyrene, which used to make many things from drinking cups to packaging material.

Contact allergens

Benzoyl peroxide is an oxidizing agent widely employed in acne topical therapy. It is also used as a polymerization catalyst of dental or industrial plastics and as a decolorizing agent of flours, oils, fats, and waxes. Irritant or allergic dermatitis may affect workers in the electronics and plastics (epoxy resins and catalysts) industries, electricians, ceramic workers, dentists and dental technicians, laboratory technicians, bakers, and acne patients. As it was contained in candles, it also induced contact dermatitis in a sacristan. Patch tests may be irritant.

Acne vulgaris

Although the precise cause of acne is unclear, it appears to be associated with at least four factors: increased sebum production, follicular keratinisation, bacterial colonisation and inflammation.
Study suggests the prevalent bacterium implicated in the clinical course of acne is Propionibacterium acnes (P acnes), a gram-positive anaerobe that normally inhabits the skin and is implicated in the inflammatory phase of acne.
Benzoyl peroxide is mainly indicated in the treatment of mild to moderate acne and is often prescribed in conjunction with oral antibiotics (erythromycin or clindamycin) in the treatment of moderate to severe acne.

Chemical Properties

white powder or crystals

Active Ingredients for Acne Medications

Benzoyl peroxide used in 2.5, 5, and 10 percent concentrations, depending on the acne severity. Usually these are in a gel spreading agent, but they can also be in a cream base or a drying paste. Benzoyl peroxide is a keratolytic, which means “keratin-dissolving” and works by loosening dead cells stuck in the follicles. It also releases oxygen in the follicle. Because acne bacteria are anaerobic, they cannot survive in the presence of oxygen. Benzoyl peroxide essentially works both as an interfollicular exfoliant and as an antibacterial.

Purification Methods

Dissolve benzoyl peroxide in CHCl3 at room temperature and precipitate it by adding an equal volume of MeOH or pet ether. Similarly it is precipitated from acetone by adding two volumes of distilled water. It has also been crystallised from 50% MeOH and from diethyl ether. Dry it under vacuum at room temperature for 24hours. Store it in a desiccator in the dark at 0o. When purifying in the absence of water it can be EXPLOSIVE, and operations should be done on a very small scale with adequate protection. Large amounts should be kept moist with water and stored in a refrigerator. [Kim et al. J Org Chem 52 3691 1987, Beilstein 9 IV 777.]
InChI:InChI=1/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H

94-36-0 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Aldrich (513466)  Luperox®ATC50,Benzoylperoxide  ~50 wt. % in tricresyl phosphate 94-36-0 513466-500ML 981.63CNY Detail
Aldrich (517909)  Luperox®A75,Benzoylperoxide  75%, remainder water 94-36-0 517909-500G 1,244.88CNY Detail
Aldrich (517909)  Luperox®A75,Benzoylperoxide  75%, remainder water 94-36-0 517909-100G 360.36CNY Detail
Aldrich (517909)  Luperox®A75,Benzoylperoxide  75%, remainder water 94-36-0 517909-5G 300.69CNY Detail
Aldrich (632651)  Luperox®A70S,Benzoylperoxide  70%, remainder water 94-36-0 632651-500G 1,444.95CNY Detail
Alfa Aesar (L13174)  Benzoyl peroxide, 97% (dry wt.), wet with 25% water    94-36-0 1000g 979.0CNY Detail
Alfa Aesar (L13174)  Benzoyl peroxide, 97% (dry wt.), wet with 25% water    94-36-0 250g 328.0CNY Detail
Alfa Aesar (L13174)  Benzoyl peroxide, 97% (dry wt.), wet with 25% water    94-36-0 50g 157.0CNY Detail
TCI America (B3152)  Benzoyl Peroxide (wetted with ca. 25% Water)  >75.0%(T) 94-36-0 25g 80.00CNY Detail

94-36-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Benzoyl peroxide

1.2 Other means of identification

Product number -
Other names benzoyl benzenecarboperoxoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food Additives: BLEACHING_AGENT; FLOUR_TREATMENT_AGENT
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:94-36-0 SDS

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