Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate

Base Information

• Chemical Name: Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate
• CAS No.: 118679-74-6
• Molecular Formula: C₄₀H₃₄N₂O₁₀S
• Molecular Weight: 734.783

Synonyms:Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate

Chemical Property of Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate

Chemical Property:

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Technology Process of Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate

There total 1 articles about Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(6R,7R)-benzhydryl 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate (35246-64-1) + 3,4-(diacetyloxy)benzoyl chloride (57929-25-6) + 3,4-Diacetoxy-benzoesaeure (58534-64-8) → Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate (118679-74-6)

Guidance literature:

With pyridine; In dichloromethane; cyclohexane; water; ethyl acetate;

Reference yield:

Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate (118679-74-6) → Sodium (6R,7R)-3-(3,4-Dihydroxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate (118679-78-0)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; dichloromethane; water; methoxybenzene;

Reference yield:

Diphenylmethyl (6R,7R)-3-(3,4-Diacetoxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate (118679-74-6) → Diphenylmethyl (6R,7R)-7-amino-3-(3,4-diacetoxybenzoyloxy)methylceph-3-em-4-carboxylate (118679-75-7)

Guidance literature:

With 4-methyl-morpholine; phosphorus pentachloride; In methanol; dichloromethane; water; ethyl acetate;

upstream raw materials:

(6R,7R)-benzhydryl 3-(hydroxymethyl)-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

3,4-(diacetyloxy)benzoyl chloride

3,4-Diacetoxy-benzoesaeure

Downstream raw materials:

Diphenylmethyl (6R,7R)-7-amino-3-(3,4-diacetoxybenzoyloxy)methylceph-3-em-4-carboxylate

Sodium (6R,7R)-3-(3,4-Dihydroxybenzoyloxy)methyl-7-(2-phenylacetamido)ceph-3-em-4-carboxylate

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