(R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide

Base Information

• Chemical Name: (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide
• CAS No.: 258356-38-6
• Molecular Formula: C₁₃H₂₂OSSi
• Molecular Weight: 254.469
• Mol file: 258356-38-6.mol

Synonyms:(R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide

Chemical Property of (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide

There total 1 articles about (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-(trimethylsilyl)propylmagnesium chloride + (-)-menthyl (S)-p-toluenesulfinate → (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide (258356-38-6)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 0.416667h;

DOI:10.1021/jo9913560

Reference yield: 76.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide (258356-38-6) → 1-{(1S)-1-[(R)-p-tolylsulfinyl]-3-(trimethylsilyl)propyl}-1-cyclohexanol + 1-{(1R)-1-[(R)-p-tolylsulfinyl]-3-(trimethylsilyl)propyl}-1-cyclohexanol

Guidance literature:

(R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.666667h;

cyclohexanone; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h; Further stages.;

DOI:10.1021/jo9913560

Reference yield: 59.0%

acetone (67-64-1) + (R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide (258356-38-6) → (3R)-2-methyl-3-[(R)-p-tolylsulfinyl]-5-(trimethylsilyl)-2-pentanol + (3S)-2-methyl-3-[(R)-p-tolylsulfinyl]-5-(trimethylsilyl)-2-pentanol

Guidance literature:

(R)-p-tolyl 3-(trimethylsilyl)propyl sulfoxide; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.666667h;

acetone; In tetrahydrofuran; hexane; at -78 ℃; for 0.0833333h; Further stages.;

DOI:10.1021/jo9913560