cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol

Base Information

• Chemical Name: cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol
• CAS No.: 97826-91-0
• Molecular Formula: C₁₇H₂₂O₃
• Molecular Weight: 274.36
• Mol file: 97826-91-0.mol

Synonyms:cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol

Chemical Property of cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol

There total 2 articles about cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol 1-acetate (124603-86-7) → cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol (97826-91-0)

Guidance literature:

With potassium carbonate; In methanol; for 1.5h;

DOI:10.1021/jo00294a030

Reference yield:

cis-2-(acetyloxy)-1-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>ethanone (97826-90-9) → cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol (97826-91-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / -100 °C

2: K₂CO₃ / methanol / 25 °C

With potassium carbonate; In tetrahydrofuran; methanol;

DOI:10.1021/jo00218a039

Reference yield:

cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol (97826-91-0) → 3-tert-Butoxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-cyclohex-3-enyl]-propane-1,2-diol (124603-88-9) + 2(S)-<2(R)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranemethanol (97905-62-9) + 2(S)-<2(S)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranemethanol (97826-98-7,97905-62-9)

Guidance literature:

With titanium(IV) tetrabutoxide; tert.-butylhydroperoxide; diethyl (2R,3R)-tartrate; In dichloromethane; at -23 ℃; for 5.5h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00294a030

upstream raw materials:

cis-2-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>-2-propen-1-ol 1-acetate

cis-2-(acetyloxy)-1-<2-<(4-methoxybenzyl)oxy>-3-cyclohexen-1-yl>ethanone

Downstream raw materials:

3-tert-Butoxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-cyclohex-3-enyl]-propane-1,2-diol

2(S)-<2(R)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranemethanol

2(S)-<2(S)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranemethanol

2(R)-<2(R)-<(4-methoxybenzyl)oxy>-3-cyclohexen-1(S)-yl>oxiranecarbaldehyde