(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Base Information

Chemical Name:(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester
CAS No.:103321-46-6
Molecular Formula:C₄₄H₆₆N₁₂O₉
Molecular Weight:907.083
Hs Code.:

(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Synonyms:(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Suppliers and Price of (S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

There total 7 articles about (S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1489-76-5
4-(4-Benzyloxycarbonylamino-butyrylamino)-butyric acid

: 103321-46-6
(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: Et₃N / dimethylformamide / 0.33 h

2: Et₃N / dimethylformamide / 0.5 h

3: 97 percent / Ba(OH)2.8H₂O / ethanol; H₂O / Ambient temperature

4: 100 percent / diphenylphosphoryl azide (DPPA), Et₃N / dimethylformamide / Ambient temperature

5: 98 percent / HCl (gas), H₂ / 5percent Pd/C / methanol / 1 h

6: 1.) diethyl phosphorocyanidate (DEPC), Et₃N, 2.) Et₃N / 1.) DMF, 2.) DMF, 3 days

With hydrogenchloride; barium dihydroxide; diethyl cyanophosphonate; diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00160a014

Reference yield:

: 90139-76-7
4-(4-Benzyloxycarbonylamino-butyrylamino)-butyric acid methyl ester

: 103321-46-6
(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 97 percent / Ba(OH)2.8H₂O / ethanol; H₂O / Ambient temperature

2: Et₃N / dimethylformamide / 0.33 h

3: Et₃N / dimethylformamide / 0.5 h

4: 97 percent / Ba(OH)2.8H₂O / ethanol; H₂O / Ambient temperature

5: 100 percent / diphenylphosphoryl azide (DPPA), Et₃N / dimethylformamide / Ambient temperature

6: 98 percent / HCl (gas), H₂ / 5percent Pd/C / methanol / 1 h

7: 1.) diethyl phosphorocyanidate (DEPC), Et₃N, 2.) Et₃N / 1.) DMF, 2.) DMF, 3 days

With hydrogenchloride; barium dihydroxide; diethyl cyanophosphonate; diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00160a014

Reference yield:

: C₂₁H₃₀N₂O₇

: 103321-46-6
(S)-2-(4-{4-[4-(4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-butyrylamino)-butyrylamino]-butyrylamino}-butyrylamino)-pentanedioic acid di-tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: Et₃N / dimethylformamide / 0.5 h

2: 97 percent / Ba(OH)2.8H₂O / ethanol; H₂O / Ambient temperature

3: 100 percent / diphenylphosphoryl azide (DPPA), Et₃N / dimethylformamide / Ambient temperature

4: 98 percent / HCl (gas), H₂ / 5percent Pd/C / methanol / 1 h

5: 1.) diethyl phosphorocyanidate (DEPC), Et₃N, 2.) Et₃N / 1.) DMF, 2.) DMF, 3 days

With hydrogenchloride; barium dihydroxide; diethyl cyanophosphonate; diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In methanol; ethanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00160a014