N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

Base Information

Chemical Name:N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine
CAS No.:1025925-64-7
Molecular Formula:C₂₀H₂₉F₃N₆
Molecular Weight:410.486
Hs Code.:

<i>N</i>-butyl-<i>N</i>''-(4-dimethylamino-2-trifluoromethyl-phenyl)-<i>N</i>-ethyl-2-methyl-pyrimidine-4,5,6-triamine

Synonyms:N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

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Technology Process of N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

There total 6 articles about N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026964-62-4
N-butyl-N'-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-5-nitro-pyrimidine-4,6-diamine

: 1025925-64-7
N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

Guidance literature:: With ammonium hydroxide; sodium dithionite; In 1,4-dioxane; water; at 25 ℃;
DOI:10.1021/jm980224g

Reference yield:

: 13360-63-9
N-ethylbutylamine

: 1025925-64-7
N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / acetone / Ambient temperature

2: Na₂S₂O₄, NH₄OH / dioxane; H₂O / 25 °C

With ammonium hydroxide; sodium dithionite; triethylamine; In 1,4-dioxane; water; acetone;
DOI:10.1021/jm980224g

Reference yield:

: 13162-43-1
4,6-dichloro-2-methyl-5-nitropyrimidine

: 1025925-64-7
N-butyl-N''-(4-dimethylamino-2-trifluoromethyl-phenyl)-N-ethyl-2-methyl-pyrimidine-4,5,6-triamine

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylsulfoxide / Ambient temperature

2: POCl₃ / Heating

3: Et₃N / acetone / Ambient temperature

4: Na₂S₂O₄, NH₄OH / dioxane; H₂O / 25 °C

With ammonium hydroxide; sodium dithionite; triethylamine; trichlorophosphate; In 1,4-dioxane; water; dimethyl sulfoxide; acetone;
DOI:10.1021/jm980224g