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  • 13360-63-9 Structure
  • Basic information

    1. Product Name: Ethylbutylamine
    2. Synonyms: Butyl(ethyl)amin;N-Ethyl-n-butylamine,99%;N-Ethyl-1-butylamine, 99%;N-Ethyl-n-butylaMine, 99% 250GR;N-Ethylbutylamine >=98.0%;N-Ethylbutylamine;n-ethyl-1-butanamin;N-Ethyl-1-butanamine
    3. CAS NO:13360-63-9
    4. Molecular Formula: C6H15N
    5. Molecular Weight: 101.19
    6. EINECS: 236-415-0
    7. Product Categories: Amines;C2 to C6;Nitrogen Compounds
    8. Mol File: 13360-63-9.mol
    9. Article Data: 18
  • Chemical Properties

    1. Melting Point: -87.87°C (estimate)
    2. Boiling Point: 108 °C(lit.)
    3. Flash Point: 18 °C
    4. Appearance: /
    5. Density: 0.74 g/mL at 25 °C(lit.)
    6. Vapor Density: 3.5 (vs air)
    7. Vapor Pressure: 18 mm Hg ( 20 °C)
    8. Refractive Index: n20/D 1.405(lit.)
    9. Storage Temp.: Flammables area
    10. Solubility: N/A
    11. PKA: 10.84±0.19(Predicted)
    12. Water Solubility: partly soluble
    13. BRN: 1731324
    14. CAS DataBase Reference: Ethylbutylamine(CAS DataBase Reference)
    15. NIST Chemistry Reference: Ethylbutylamine(13360-63-9)
    16. EPA Substance Registry System: Ethylbutylamine(13360-63-9)
  • Safety Data

    1. Hazard Codes: F,C
    2. Statements: 11-22-34
    3. Safety Statements: 16-26-36/37/39-45-33
    4. RIDADR: UN 2733 3/PG 2
    5. WGK Germany: 1
    6. RTECS: EO4880000
    7. TSCA: Yes
    8. HazardClass: 3
    9. PackingGroup: II
    10. Hazardous Substances Data: 13360-63-9(Hazardous Substances Data)

13360-63-9 Usage

Description

Ethylbutylamine is a colorless to light yellow liquid with an ammonia-like odor. It is insoluble in water and less dense than water, with a flash point of 65°F. The vapors of this compound are much heavier than air, and both the liquid and its vapors can strongly irritate the skin, eyes, and mucous membranes. Contact with the liquid may cause burns.

Uses

Used in Chemical Synthesis:
Ethylbutylamine is used as an intermediate in the chemical synthesis industry for the production of various compounds and materials. Its ability to react with other chemicals makes it a versatile building block in the creation of different products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethylbutylamine is used as a building block for the synthesis of various drugs and medications. Its chemical properties allow it to be incorporated into the structure of pharmaceutical compounds, potentially enhancing their efficacy and performance.
Used in Agrochemical Industry:
Ethylbutylamine is also utilized in the agrochemical industry as an intermediate for the development of pesticides, herbicides, and other agricultural chemicals. Its role in these applications is to help create more effective and targeted products for crop protection and management.
Used in Surface Treatments:
In the surface treatment industry, Ethylbutylamine is used as a component in the formulation of various coatings, adhesives, and sealants. Its chemical properties contribute to the overall performance and durability of these materials, making them more suitable for their intended applications.
Used in Corrosion Inhibition:
Ethylbutylamine is employed in the oil and gas industry as a corrosion inhibitor. Its chemical properties help to protect metal surfaces from corrosion, extending the lifespan of pipelines, storage tanks, and other equipment used in the extraction, transportation, and processing of oil and gas.
Used in Dyes and Pigments:
In the dyes and pigments industry, Ethylbutylamine is used as an intermediate for the synthesis of various colorants. Its chemical structure allows it to be incorporated into the production of dyes and pigments, resulting in a wide range of colors and shades for various applications, including textiles, plastics, and printing inks.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

Ethylbutylamine can react vigorously with oxidizing materials . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Flammable, dangerous fire risk. Toxic by ingestion.

Health Hazard

INHALATION: Irritation of mucous membranes and lungs. EYES: Irritation. Corrosive, may cause blindness - Irreversible. SKIN: Irritation. Corrosive. INGESTION: Nausea and salivation.

Check Digit Verification of cas no

The CAS Registry Mumber 13360-63-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,6 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13360-63:
(7*1)+(6*3)+(5*3)+(4*6)+(3*0)+(2*6)+(1*3)=79
79 % 10 = 9
So 13360-63-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H15N/c1-3-5-6-7-4-2/h7H,3-6H2,1-2H3/p+1

13360-63-9 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (B22881)  N-Ethyl-1-butylamine, 99%   

  • 13360-63-9

  • 250g

  • 876.0CNY

  • Detail
  • Alfa Aesar

  • (B22881)  N-Ethyl-1-butylamine, 99%   

  • 13360-63-9

  • 1000g

  • 1452.0CNY

  • Detail

13360-63-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethylbutylamine

1.2 Other means of identification

Product number -
Other names 1-Butanamine, N-ethyl-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13360-63-9 SDS

13360-63-9Synthetic route

(4-{tris[2-(perfluorohexyl)ethyl]silyl}benzyl) (butyl)(ethyl)carbamate

(4-{tris[2-(perfluorohexyl)ethyl]silyl}benzyl) (butyl)(ethyl)carbamate

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 16h;80%
tributyl borane
122-56-5

tributyl borane

O-(p-toluenesulfonyl)-N-ethylhydroxylamine
81375-29-3

O-(p-toluenesulfonyl)-N-ethylhydroxylamine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
In tetrahydrofuran for 2h; Ambient temperature;77%
methyllithium
917-54-4

methyllithium

Butyl-phenylsulfanylmethyl-amine; hydrochloride
33704-65-3

Butyl-phenylsulfanylmethyl-amine; hydrochloride

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
In diethyl ether at -60℃;76%
ethylamine
75-04-7

ethylamine

N-butylamine
109-73-9

N-butylamine

A

tributyl-amine
102-82-9

tributyl-amine

B

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

C

N,N-diethylbutylamine
4444-68-2

N,N-diethylbutylamine

D

di-n-butylethylamine
4458-33-7

di-n-butylethylamine

E

dibutylamine
111-92-2

dibutylamine

F

diethylamine
109-89-7

diethylamine

G

triethylamine
121-44-8

triethylamine

Conditions
ConditionsYield
With hydrogen at 200℃; under 6000.6 Torr; Reagent/catalyst; Temperature;A n/a
B 60.7%
C n/a
D n/a
E n/a
F n/a
G n/a
ethylamine
75-04-7

ethylamine

butan-1-ol
71-36-3

butan-1-ol

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With hydrogen at 150℃; under 3750.38 Torr; for 8h; Temperature; Pressure; Reagent/catalyst;55.3%
With hydrogen; nickel at 150℃;
propyl cyanide
109-74-0

propyl cyanide

ethanol
64-17-5

ethanol

A

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

B

(butylidene)butylamine
4853-56-9

(butylidene)butylamine

C

N-butylamine
109-73-9

N-butylamine

Conditions
ConditionsYield
With Co(9.8%)/SiO2 catalyst; hydrogen at 129.84℃; under 9750.98 Torr; Reagent/catalyst; Temperature;A 30.5%
B 25.6%
C 42.3%
N,N-dichloro-n-butylamine
14925-83-8

N,N-dichloro-n-butylamine

diethylzinc
557-20-0

diethylzinc

A

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

B

N-butylamine
109-73-9

N-butylamine

Conditions
ConditionsYield
With Petroleum ether
ethyl-butyliden-amine
1611-12-7

ethyl-butyliden-amine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With nickel; Petroleum ether at 75℃; under 154457 Torr; Hydrogenation;
With ethanol; sodium
With ethanol; platinum Hydrogenation;
N-benzyl-N-ethylbutan-1-amine
77228-69-4

N-benzyl-N-ethylbutan-1-amine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With platinum(IV) oxide; acetic acid at 65 - 75℃; Hydrogenolyse;
ethylamine
75-04-7

ethylamine

butyraldehyde
123-72-8

butyraldehyde

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With ethanol; platinum Hydrogenation;
(i), (ii) H2, Pd-C, EtOH; Multistep reaction;
With potassium hydroxide; dipotassium hydrogenphosphate; phosphoric acid at 10 - 12℃; for 4h; electrochemical reductive amination, lead cathode, current density 0.05 A/cm2, pH 12; Yield given;
ethylamine
75-04-7

ethylamine

crotonaldehyde
123-73-9

crotonaldehyde

A

N,N'-Diaethyl-1-methyl-1,3-propandiamin
32280-46-9

N,N'-Diaethyl-1-methyl-1,3-propandiamin

B

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With methanol; nickel at 125℃; Hydrogenation;
ethylamine
75-04-7

ethylamine

crotonaldehyde
123-73-9

crotonaldehyde

A

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

B

N,N-diethylbutylamine
4444-68-2

N,N-diethylbutylamine

Conditions
ConditionsYield
With methanol; nickel at 125℃; Hydrogenation;
ethanol
64-17-5

ethanol

N-butylamine
109-73-9

N-butylamine

A

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

B

dibutylamine
111-92-2

dibutylamine

Conditions
ConditionsYield
With nickel
Acetaldehyd-butylimin
6898-74-4

Acetaldehyd-butylimin

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With ethanol; platinum Hydrogenation;
1-bromo-butane
109-65-9

1-bromo-butane

diethyl N-ethylphosphoramidate
1946-09-4

diethyl N-ethylphosphoramidate

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
(i) aq. NaOH, HSO4, (ii) HCl; Multistep reaction;
butyl-ethyl-tetrahydropyran-2-yl-amine
26683-07-8

butyl-ethyl-tetrahydropyran-2-yl-amine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
(hydrolysis);
ethene
74-85-1

ethene

N-butylamine
109-73-9

N-butylamine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With N,N,N,N,-tetramethylethylenediamine at 130 - 150℃; under 183877 Torr;
phenyl-trichloromethyl-phosphinic acid ethyl ester
54944-19-3

phenyl-trichloromethyl-phosphinic acid ethyl ester

N-butylamine
109-73-9

N-butylamine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

diethyl sulfate
64-67-5

diethyl sulfate

N-benzylidenebutan-1-amine
1077-18-5

N-benzylidenebutan-1-amine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

triethyl borane
97-94-9

triethyl borane

n-butylazide
7332-00-5

n-butylazide

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
In xylene for 6h; Heating;72 % Chromat.
In xylene for 6h; Rate constant; Heating;72 % Chromat.
C24H29NP(1+)*I(1-)
102711-05-7

C24H29NP(1+)*I(1-)

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With water; hydroxide
(R)-5-Butylaminomethyl-2,7,8-trimethyl-2-((4R,8R)-4,8,12-trimethyl-tridecyl)-chroman-6-ol; hydrobromide

(R)-5-Butylaminomethyl-2,7,8-trimethyl-2-((4R,8R)-4,8,12-trimethyl-tridecyl)-chroman-6-ol; hydrobromide

EtHal

EtHal

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With sodium hydroxide 1.) CH2Cl2, -20 deg C, 10 min, 2.) room temperature, 30 min, 3.) 70 deg C, 1 h; Yield given. Multistep reaction;
(CO)5CrC(Me)(n-butylamine)

(CO)5CrC(Me)(n-butylamine)

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With Li{AlH4}
piperidine
110-89-4

piperidine

C14H21NO
885663-12-7

C14H21NO

A

N-(4-methylbenzoyl)piperidine
13707-23-8

N-(4-methylbenzoyl)piperidine

B

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

Conditions
ConditionsYield
With Al2(NMe2)6 In toluene at 90℃; for 16h; Equilibrium constant;
C14H21NO
885663-12-7

C14H21NO

benzyl-methyl-amine
103-67-3

benzyl-methyl-amine

A

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

B

4-methyl-N-benzyl-N-methylbenzamide
57409-40-2

4-methyl-N-benzyl-N-methylbenzamide

Conditions
ConditionsYield
With Al2(NMe2)6 In toluene at 90℃; for 16h; Equilibrium constant;
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid
287721-05-5

4-[phenyl(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)amino]benzoic acid

N-butyl-N-ethyl-4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-benzamide

N-butyl-N-ethyl-4-[(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-phenyl-amino]-benzamide

Conditions
ConditionsYield
With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate Acylation;100%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

N-[3-(trimethylamino)methyl-4-hydroxyphenyl]-1,8-naphthalimide iodide
1286315-70-5

N-[3-(trimethylamino)methyl-4-hydroxyphenyl]-1,8-naphthalimide iodide

N-[3-(butylethylamino)methyl-4-hydroxyphenyl]-1,8-naphthalimide
1286315-76-1

N-[3-(butylethylamino)methyl-4-hydroxyphenyl]-1,8-naphthalimide

Conditions
ConditionsYield
In water; acetonitrile at 25℃; for 0.166667h; Quantum yield; Inert atmosphere; Irradiation;100%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

4-N-(2,4,6-trimethylphenyl)-6-chloro-2-methyl-5-nitropyrimidin-4-amine
175140-70-2

4-N-(2,4,6-trimethylphenyl)-6-chloro-2-methyl-5-nitropyrimidin-4-amine

4-N-(2,4,6-trimethylphenyl)-6-(N-n-butylethylamino)-2-methyl-5-nitropyrimidin-4-amine
175139-13-6

4-N-(2,4,6-trimethylphenyl)-6-(N-n-butylethylamino)-2-methyl-5-nitropyrimidin-4-amine

Conditions
ConditionsYield
With triethylamine In acetone Ambient temperature;98%
carbon disulfide
75-15-0

carbon disulfide

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

(N-ethyl-N'-n-butyldithiocarbamato) sodium
163594-66-9

(N-ethyl-N'-n-butyldithiocarbamato) sodium

Conditions
ConditionsYield
Stage #1: N-ethylbutylamine With sodium hydroxide In methanol; water at 0℃; for 0.333333h;
Stage #2: carbon disulfide In methanol; water at 20℃;
98%
Stage #1: N-ethylbutylamine With sodium hydroxide In methanol; water at 0℃; for 0.333333h;
Stage #2: carbon disulfide In methanol; water at 0 - 20℃;
98%
With sodium hydroxide In water98%
With sodium hydroxide In water for 2h; Cooling with ice;
2-ethynylpyridine
1945-84-2

2-ethynylpyridine

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

(E)-N-ethyl-N-(2-(pyridine-2-yl)vinyl)butan-1-amine

(E)-N-ethyl-N-(2-(pyridine-2-yl)vinyl)butan-1-amine

Conditions
ConditionsYield
With ethylene glycol at 150℃; for 8h; Inert atmosphere; Sealed tube; Green chemistry; regioselective reaction;98%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

3-[2-bromo-4-(1-methylethyl)phenyl]-7-chloro-5-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine
169882-29-5

3-[2-bromo-4-(1-methylethyl)phenyl]-7-chloro-5-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine

[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-butyl-ethyl-amine

[3-(2-bromo-4-isopropyl-phenyl)-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-butyl-ethyl-amine

Conditions
ConditionsYield
With triethylamine In ethanol Heating;97%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

1-methyl-3-{4-[tris-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-silanyl]-benzyloxycarbonyl}-3H-imidazol-1-ium; trifluoro-methanesulfonate

1-methyl-3-{4-[tris-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-silanyl]-benzyloxycarbonyl}-3H-imidazol-1-ium; trifluoro-methanesulfonate

(4-{tris[2-(perfluorohexyl)ethyl]silyl}benzyl) (butyl)(ethyl)carbamate

(4-{tris[2-(perfluorohexyl)ethyl]silyl}benzyl) (butyl)(ethyl)carbamate

Conditions
ConditionsYield
With dmap In dichloromethane at 20℃; for 16h;91%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

dichloromethylenedimethyliminium chloride

dichloromethylenedimethyliminium chloride

[bis-(ethylbutylamino)-dimethylguanidinium] chloride
672953-00-3

[bis-(ethylbutylamino)-dimethylguanidinium] chloride

Conditions
ConditionsYield
Stage #1: N-ethylbutylamine; dichloromethylenedimethyliminium chloride With triethylamine In dichloromethane at 0 - 20℃; for 4h;
Stage #2: With sodium hydroxide In water
Stage #3: With hydrogenchloride In diethyl ether; water pH=7;
91%
N,N'-bis[3-(trimethylammonio)methyl-4-hydroxyphenyl]-1,4,5,8-naphthalenetetracarboxylic diimide diiodide

N,N'-bis[3-(trimethylammonio)methyl-4-hydroxyphenyl]-1,4,5,8-naphthalenetetracarboxylic diimide diiodide

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

C40H44N4O6

C40H44N4O6

Conditions
ConditionsYield
Stage #1: N,N'-bis[3-(trimethylammonio)methyl-4-hydroxyphenyl]-1,4,5,8-naphthalenetetracarboxylic diimide diiodide; N-ethylbutylamine With sodium dithionite In water; acetonitrile at 25℃; for 0.5h;
Stage #2: With air In water; acetonitrile for 0.166667h; cooling; Further stages.;
90%
Phenylpropargyl aldehyde
2579-22-8

Phenylpropargyl aldehyde

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

(Z)-3-(butyl(ethyl)amino)-1-phenylprop-2-en-1-one

(Z)-3-(butyl(ethyl)amino)-1-phenylprop-2-en-1-one

Conditions
ConditionsYield
In ethanol at 60℃; for 0.25h; regioselective reaction;90%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

4-chloro-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo-[2,3-d]pyrimidine
157286-81-2

4-chloro-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo-[2,3-d]pyrimidine

butyl[2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]ethylamine

butyl[2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]ethylamine

Conditions
ConditionsYield
89%
In dimethyl sulfoxide at 130℃; for 3h;88%
carbon disulfide
75-15-0

carbon disulfide

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

indium(III) chloride
10025-82-8

indium(III) chloride

tris(N,N-ethylbutyldithiocarbamato)indium(III)
878385-08-1

tris(N,N-ethylbutyldithiocarbamato)indium(III)

Conditions
ConditionsYield
With sodium hydroxide In methanol NaOH and N,N-ethylbutylamine were dissplved in MeOH, CS2 was dropped slowly at 0°C for 1 h, InCl3 was added; ppt. was filtered, dtied in vacuo, and recrystd.; elem. anal.;89%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

7-chloro-5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
197803-09-1

7-chloro-5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine

butyl-ethyl-[5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine

butyl-ethyl-[5-methyl-3-(2,4,6-trimethyl-pyridin-3-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-amine

Conditions
ConditionsYield
With triethylamine In ethanol Heating;86%
1,4-dibromo-butane
110-52-1

1,4-dibromo-butane

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

bis(trifluoromethane)sulfonimide lithium
90076-65-6

bis(trifluoromethane)sulfonimide lithium

N-butyl-N-ethylpyrrolidinium bis(trifluoromethanesulfonyl)imide
1119616-46-4

N-butyl-N-ethylpyrrolidinium bis(trifluoromethanesulfonyl)imide

Conditions
ConditionsYield
Stage #1: 1,4-dibromo-butane; N-ethylbutylamine With potassium carbonate In water at 120℃; for 0.333333h; Autoclave; Microwave irradiation; Green chemistry;
Stage #2: bis(trifluoromethane)sulfonimide lithium In water at 20℃; for 1h; Green chemistry;
86%
1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

bis(trifluoromethane)sulfonimide lithium
90076-65-6

bis(trifluoromethane)sulfonimide lithium

N-butyl-N-ethylpiperidinium bis(trifluoromethanesulfonyl)imide
1174233-40-9

N-butyl-N-ethylpiperidinium bis(trifluoromethanesulfonyl)imide

Conditions
ConditionsYield
Stage #1: 1,5-dibromo-pentane; N-ethylbutylamine With potassium carbonate In water at 120℃; for 0.666667h; Autoclave; Microwave irradiation; Green chemistry;
Stage #2: bis(trifluoromethane)sulfonimide lithium In water at 20℃; for 1h; Green chemistry;
86%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

3-[(benzyloxy)(5-bromopentanoyl)amino]propanoic acid tert-butyl ester

3-[(benzyloxy)(5-bromopentanoyl)amino]propanoic acid tert-butyl ester

tert-butyl 3-{N-(benzyloxy)-5-[butyl(ethyl)amino]pentanamido}propanoate

tert-butyl 3-{N-(benzyloxy)-5-[butyl(ethyl)amino]pentanamido}propanoate

Conditions
ConditionsYield
In acetonitrile Reflux;86%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

C18H16NO2P
102536-14-1

C18H16NO2P

N-Butyl-N-ethyl-N'-phenyl-hydrazine
102536-06-1

N-Butyl-N-ethyl-N'-phenyl-hydrazine

Conditions
ConditionsYield
85%
1-(propa-1,2-dien-1-yl)pyrrolidin-2-one
17426-48-1

1-(propa-1,2-dien-1-yl)pyrrolidin-2-one

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

C13H24N2O

C13H24N2O

Conditions
ConditionsYield
With tetrakis(actonitrile)copper(I) hexafluorophosphate In tetrahydrofuran at 20℃; for 18h; Inert atmosphere; diastereoselective reaction;85%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

1-ethyl-4-ethynylbenzene
40307-11-7

1-ethyl-4-ethynylbenzene

(E)-N-ethyl-N-(4-ethylstyryl)butan-1-amine

(E)-N-ethyl-N-(4-ethylstyryl)butan-1-amine

Conditions
ConditionsYield
With ethylene glycol at 150℃; for 8h; Inert atmosphere; Sealed tube; Green chemistry; regioselective reaction;85%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

2-chloro-1,3-dinitro-5-(trifluoromethylthio)benzene
557099-37-3

2-chloro-1,3-dinitro-5-(trifluoromethylthio)benzene

2,6-dinitro-4-trifluoromethylthio-N-ethyl-N-butylaniline

2,6-dinitro-4-trifluoromethylthio-N-ethyl-N-butylaniline

Conditions
ConditionsYield
In ethanol for 0.5h;84%
In methanol for 0.5h; Heating;84%
N-ethylbutylamine
13360-63-9

N-ethylbutylamine

1-chloro-2,6-dinitrobenzene-4-(pentafluorosulfanyl)benzene
842158-34-3

1-chloro-2,6-dinitrobenzene-4-(pentafluorosulfanyl)benzene

2,6-dinitro-4-pentafluorosulfanyl-N-ethyl-N-butylaniline

2,6-dinitro-4-pentafluorosulfanyl-N-ethyl-N-butylaniline

Conditions
ConditionsYield
In ethanol for 0.5h;84%

13360-63-9Relevant articles and documents

Selective one-pot synthesis of asymmetric secondary amines via N-alkylation of nitriles with alcohols

Segobia,Trasarti,Apesteguía

, p. 178 - 185 (2019/11/13)

The synthesis of asymmetric secondary amines (ASA) is commonly achieved by N-alkylation of primary amines with alcohols. Here, we investigated the ASA synthesis via the direct amination of alcohols with nitriles, which avoids the synthesis, separation and purification of the primary amines in a first step. Specifically, the ASA synthesis via N-alkylation of butyronitrile (BN) with primary (n-propanol, iso-butanol and n-octanol) and secondary (2‐propanol, 2‐butanol and 2‐octanol) alcohols was studied on SiO2-supported Co, Ni and Ru catalysts. Competitive BN hydrogenation‐condensation reactions formed dibutylamine (the symmetric secondary amine) and tertiary amines as main secondary products. On Co/SiO2, the ASA selectivities for BN/primary alcohol reactions were between 49 and 58% at complete BN conversion, forming dibutylamine and tertiary amines as byproducts. For BN/secondary alcohol reactions, Co/SiO2 formed selectively (ASA + dibutylamine) mixtures containing 78–85% of ASA, thereby showing that the alcohol amination with nitriles is an attractive alternative route for the synthesis of valuable asymmetric secondary amines.

N-ethyl-n-butylamine production method

-

Paragraph 0047; 0050; 0053, (2017/01/05)

The invention relates to a production method of N-ethyl-n-butylamine. According to the production method, n-butanol and monoethylamine are taken as raw materials; a supported non-noble metal catalyst is used under hydrogen conditions; and amination synthe

Catalytic hydrogenation of amides to amines under mild conditions

Stein, Mario,Breit, Bernhard

supporting information, p. 2231 - 2234 (2013/03/28)

Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright

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