Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Base Information

Chemical Name:Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate
CAS No.:135145-02-7
Molecular Formula:C₂₃H₂₉NO₇
Molecular Weight:431.486
Hs Code.:

Synonyms:Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Suppliers and Price of Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

There total 4 articles about Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 52709-42-9
benzylglyoxylate

: 42419-19-2
tert-butyl 3-(2-methoxycarbonylethyl)-4-methylpyrrole-2-carboxylate

: 135145-04-9
5-Benzyloxyoxalyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

: 135145-02-7
Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Guidance literature:: With zinc(II) chloride; In dichloromethane; for 8h; Ambient temperature;
DOI:10.1021/jo00017a017

Reference yield:

: 31837-48-6
t-butyl 5-iodo-3-(2-methoxycarbonylethyl)-4-methylpyrrole-2-carboxylate

: 135145-02-7
Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / H₂, MgO / PtO₂ / methanol / 2585.7 Torr

2: 86 percent / ZnCl₂ / CH₂Cl₂ / 8 h / Ambient temperature

With hydrogen; magnesium oxide; zinc(II) chloride; platinum(IV) oxide; In methanol; dichloromethane;
DOI:10.1021/jo00017a017

Reference yield:

: 622-00-4
dibenzyl (2R,3R)-2,3-dihydroxybutanedioate

: 135145-02-7
Benzyl α-Hydroxy-α-(5-(tert-butoxycarbonyl)-4-(2'-(methoxycarbonyl)ethyl)-3-methylpyrrol-2-yl)acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / periodic acid dihydrate / diethyl ether / 0.25 h / Ambient temperature

2: 86 percent / ZnCl₂ / CH₂Cl₂ / 8 h / Ambient temperature

With periodic acid; zinc(II) chloride; In diethyl ether; dichloromethane;
DOI:10.1021/jo00017a017