thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside

Base Information

• Chemical Name: thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside
• CAS No.: 1058019-31-0
• Molecular Formula: C₃₆H₃₆O₅S
• Molecular Weight: 580.745
• Mol file: 1058019-31-0.mol

Synonyms:thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside

Chemical Property of thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside

There total 1 articles about thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranoside (38184-12-2,120403-26-1,87470-73-3) + propargyl bromide (106-96-7) → thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside (1058019-31-0)

Guidance literature:

phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranoside; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;

propargyl bromide; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; toluene; mineral oil; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1055/s-0036-1591902

Reference yield: 100.0%

thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside (1058019-31-0) + 4-acetoxybenzyl alcohol (6309-46-2) → C39H40O8

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; In dichloromethane; at -40 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2008.06.081

Reference yield: 16.0%

thiophenyl-2,3,4-tris-O-benzyl-6-O-propargyl-β-D-galactopyranoside (1058019-31-0) + α-azido-L-serine tetradecyl amide → α-azido-O-(2,3,4-tri-O-benzyl-6-O-propargyl-α-D-galactopyranosyl)-L-serine tetradecyl amide + α-azido-O-(2,3,4-tri-O-benzyl-6-O-propargyl-β-D-galactopyranosyl)-L-serine tetradecyl amide

Guidance literature:

With N-iodo-succinimide; trifluorormethanesulfonic acid; In tetrahydrofuran; at 20 ℃; for 18h; Molecular sieve; Darkness; Inert atmosphere;

DOI:10.1055/s-0036-1591902

upstream raw materials:

phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranoside

propargyl bromide

Downstream raw materials:

C₅₈H₆₂O₁₁

C₅₈H₆₂O₁₁