Technology Process of phenyl 2,3-di-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzoyl-1-thio-β-D-xylopyranoside
There total 3 articles about phenyl 2,3-di-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-2,3-di-O-benzoyl-1-thio-β-D-xylopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
phenyl 2,3-di-O-benzyl-4,6-O-benzylidene-β-D-mannopyranosyl-(1->4)-2,3-O-isopropylidene-1-thio-β-D-xylopyranoside;
With
acetic acid;
at 65 ℃;
for 3h;
benzoyl chloride;
With
pyridine;
at 0 ℃;
for 2h;
DOI:10.1021/jo201780e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 0.5 h / -65 - -60 °C / Molecular sieve; Inert atmosphere
1.2: 0.08 h / -78 °C / Molecular sieve; Inert atmosphere
1.3: 2.5 h / -60 °C / Molecular sieve; Inert atmosphere
2.1: acetic acid / 3 h / 65 °C
2.2: 2 h / 0 °C
With
1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; acetic acid; 2,4,6-tri-tert-butylpyrimidine;
In
dichloromethane;
DOI:10.1021/jo201780e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; 2,4,6-tri-tert-butylpyrimidine / dichloromethane / 0.5 h / -65 - -60 °C / Molecular sieve; Inert atmosphere
1.2: 0.08 h / -78 °C / Molecular sieve; Inert atmosphere
1.3: 2.5 h / -60 °C / Molecular sieve; Inert atmosphere
2.1: acetic acid / 3 h / 65 °C
2.2: 2 h / 0 °C
With
1-benzenesulfinyl piperidine; trifluoromethylsulfonic anhydride; acetic acid; 2,4,6-tri-tert-butylpyrimidine;
In
dichloromethane;
DOI:10.1021/jo201780e
