5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole

Base Information

• Chemical Name: 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole
• CAS No.: 154423-34-4
• Molecular Formula: C₃₃H₂₅BrN₄
• Molecular Weight: 557.492
• Mol file: 154423-34-4.mol

Synonyms:C₃₃H₂₅BrN₄

Chemical Property of 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole

Chemical Property:

• Vapor Pressure: 7.11E-20mmHg at 25°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole

There total 4 articles about 5-[4-[4-(bromomethyl)phenyl]phenyl]-1-trityl-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C33H26N4 (1429045-73-7) → C33H25BrN4 (154423-34-4)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;

DOI:10.1016/j.bmc.2013.01.067

Reference yield:

tributyl(p-tolyl)stannane (31614-66-1) → C33H25BrN4 (154423-34-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / N,N-dimethyl-formamide / Inert atmosphere

2.1: sodium azide; tributyltin chloride / toluene / 70 h / 115 °C / Inert atmosphere

2.2: 3 h / 20 °C

3.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; sodium azide; tributyltin chloride; lithium chloride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.bmc.2013.01.067

Reference yield:

4-bromobenzenecarbonitrile (623-00-7) → C33H25BrN4 (154423-34-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bis-triphenylphosphine-palladium(II) chloride; lithium chloride / N,N-dimethyl-formamide / Inert atmosphere

2.1: sodium azide; tributyltin chloride / toluene / 70 h / 115 °C / Inert atmosphere

2.2: 3 h / 20 °C

3.1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; sodium azide; tributyltin chloride; lithium chloride; dibenzoyl peroxide; In tetrachloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1016/j.bmc.2013.01.067

upstream raw materials:

tributyl(p-tolyl)stannane

4-bromobenzenecarbonitrile

p-(p-tolyl)benzonitrile

C₃₃H₂₆N₄

Downstream raw materials:

C₂₂H₁₆N₆S

C₂₃H₁₈N₆S