1-methyl-7-oxabicyclo[4.1.0]heptane

Base Information

• Chemical Name: 1-methyl-7-oxabicyclo[4.1.0]heptane
• CAS No.: 1713-33-3
• Molecular Formula: C7H12 O
• Molecular Weight: 112.172
• Hs Code.: 2932999099
• Mol file: 1713-33-3.mol

Synonyms:7-Oxabicyclo[4.1.0]heptane,1-methyl-, (?à)-;(?à)-1-Methyl-7-oxabicyclo[4.1.0]heptane;1,2-Epoxy-1-methylcyclohexane; 1-Methyl-1,2-epoxycyclohexane;1-Methyl-7-oxabicyclo[4.1.0]heptane; 1-Methylcyclohexene 1,2-oxide;1-Methylcyclohexene epoxide; 1-Methylcyclohexene oxide; NSC 12597

Chemical Property of 1-methyl-7-oxabicyclo[4.1.0]heptane

Chemical Property:

• Vapor Pressure: 10.5mmHg at 25°C
• Refractive Index: 1.4420 to 1.4460
• Boiling Point: 133.2°Cat760mmHg
• Flash Point: 23.3°C
• PSA: 12.53000
• Density: 1.01g/cm³
• LogP: 1.71790
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Methyl-1,2-epoxycyclohexane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-methyl-7-oxabicyclo[4.1.0]heptane

There total 34 articles about 1-methyl-7-oxabicyclo[4.1.0]heptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,2-epoxy-1-methylcyclohexane (1713-33-3) → (+)-(1S,2R)-1-methylcyclohexene (56246-59-4) + (R)-(+)-1-methyl-2-cyclohexen-1-ol (88494-89-7) + 1-methyl-7-oxa-bicyclo[4.1.0]heptane (1713-33-3,56246-59-4,60363-27-1,56246-60-7)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; (1S,3R,4R)-3-(N-pyrrolidinyl)methyl-2-azabicyclo[2.2.1]heptane; lithium diisopropyl amide; In tetrahydrofuran; hexane; at 0 ℃; for 4h;

DOI:10.1021/ja000545t

Reference yield: 82.0%

1-methylcyclohex-1-ene (591-49-1) → 1,2-epoxy-1-methylcyclohexane (1713-33-3) + 1-methyl-1,2-cyclohexanediol (6296-84-0)

Guidance literature:

With Oxone; 1-[(diphenyl)methyl]pyrrolidine; sodium hydrogencarbonate; In [D₃]acetonitrile; water-d2; at 20 ℃; for 2h;

DOI:10.1021/ja0004433

Reference yield: 50.0%

1-methylcyclohex-1-ene (591-49-1) → 1,2-epoxy-1-methylcyclohexane (1713-33-3) + methyl benzilate (76-89-1)

Guidance literature:

With methyl α-hydroperoxy-α,α-diphenylacetate; oxygen; In tetrachloromethane; at 60 ℃; for 16h;

upstream raw materials:

Perbenzoic acid

monoperoxyphthalic acid

1-methylcyclohex-1-ene

3-bromo-4,5-dihydro-5-hydroperoxy-4,4-dimethyl-3,5-diphenyl-3H-pyrazole

Downstream raw materials:

(+/-)-2t-dimethylamino-1-methyl-cyclohexan-r-ol

1-Methylcyclohexanol

r-1,t-1-methyl-t-2-aminocyclohexanol

trans-1-methyl-2-methoxy-cyclohexanol

Refernces

• 1、 Zadok, Elazar,Mazur, Yehuda. "Preparative Oxidation of Cycloalkanes with O(3P) Atoms. Microwave Discharge of CO2 as a Source of O(3P) Atoms.". . p. 2223 - 2225. Retrieved 1982.
• 2、 Van Laar,De Vos,Pierard,Kirsch-De Mesmaeker,Fiermans,Jacobs, Pierre A.. "Generation of singlet molecular oxygen from H2O2 with molybdate-exchanged layered double hydroxides: Effects of catalyst composition and reaction conditions". . p. 139 - 150. Retrieved 2001.
• 3、 Maurya, Abhishek,Haldar, Chanchal. "Liquid-phase oxidation of olefins with rare hydronium ion salt of dinuclear dioxido-vanadium(V) complexes and comparative catalytic studies with analogous copper complexes". . . Retrieved 2021/02/26.
• 4、 Maurya, Abhishek,Kesharwani, Neha,Kachhap, Payal,Mishra, Vivek Kumar,Chaudhary, Nikita,Haldar, Chanchal. "Polymer-anchored mononuclear and binuclear CuII Schiff-base complexes: Impact of heterogenization on liquid phase catalytic oxidation of a series of alkenes". . . Retrieved 2019/08/12.