4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol

Base Information

Chemical Name:4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol
CAS No.:53602-00-9
Molecular Formula:C₆H₈N₂O₂
Molecular Weight:140.142
Hs Code.:
DSSTox Substance ID:DTXSID90201822
Nikkaji Number:J367.139I
Wikidata:Q27088987
ChEMBL ID:CHEMBL150830
Mol file:53602-00-9.mol

Synonyms:3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole;4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridin-3-ol;4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridin-3-ol hydrobromide;THPO

Suppliers and Price of 4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
SOMATOPRIM 95.00%
5G
$ 2711.94

American Custom Chemicals Corporation
SOMATOPRIM 95.00%
1G
$ 1152.69

Total 4 raw suppliers

Chemical Property of 4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol

Chemical Property:

Vapor Pressure:4.34E-05mmHg at 25°C
Boiling Point:340.5°Cat760mmHg
Flash Point:159.7°C
PSA：58.29000
Density:1.36g/cm³
LogP:0.35470
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:140.058577502
Heavy Atom Count:10
Complexity:210

Purity/Quality:

99% ^*data from raw suppliers

SOMATOPRIM 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC2=C1ONC2=O

Technology Process of 4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol

There total 4 articles about 4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 53601-98-2
methyl 3-hydroxy-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridine-5-carboxylate

: 53602-00-9
4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol

Guidance literature:: With hydrogen bromide; In acetic acid;

Reference yield:

: 53659-15-7
6-hydroxycarbamoyl-1,4-dioxa-8-aza-spiro[4.5]decane-8-carboxylic acid methyl ester

: 53602-00-9
4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / methanol

2: aq. HBr / acetic acid

With hydrogenchloride; hydrogen bromide; In methanol; acetic acid;

Reference yield:

: 53659-13-5
1,4-dioxa-8-aza-spiro[4.5]decane-6,8-dicarboxylic acid 6-ethyl ester 8-methyl ester

: 53602-00-9
4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-ol

Guidance literature:: Multi-step reaction with 3 steps

1: NH₂OH, KOH / methanol

2: aq. HCl / methanol

3: aq. HBr / acetic acid

With hydrogenchloride; potassium hydroxide; hydrogen bromide; hydroxylamine; In methanol; acetic acid;