4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester

Base Information

Chemical Name:4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester
CAS No.:53601-95-9
Molecular Formula:C10H15NO5
Molecular Weight:229.233
Hs Code.:
DSSTox Substance ID:DTXSID401173361
Mol file:53601-95-9.mol

Synonyms:53601-95-9;4-oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester;SCHEMBL10654314;DTXSID401173361;DB-358479;1,3-Piperidinedicarboxylic acid, 4-oxo-, 3-ethyl 1-methyl ester

Suppliers and Price of 4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:229.09502258
Heavy Atom Count:16
Complexity:302

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1CN(CCC1=O)C(=O)OC

Technology Process of 4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester

There total 1 articles about 4-Oxo-piperidine-1,3-dicarboxylic acid 3-ethyl ester 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141-52-6
sodium ethanolate

: 53601-95-9
3-ethyl-1-methyl-4-oxopiperidine-1,3-dicarboxylate

Guidance literature:

Reference yield: 71.0%

: 53601-95-9
3-ethyl-1-methyl-4-oxopiperidine-1,3-dicarboxylate

: 100-46-9
benzylamine

: 76508-64-0
ethyl 1-methoxycarbonyl-4-benzylamino-1,2,5,6-tetrahydropyridine-3-carboxylate

Guidance literature:: With 3 A molecular sieve; In toluene; for 20h; Heating;
DOI:10.3891/acta.chem.scand.34b-0319

Reference yield:

: 53601-95-9
3-ethyl-1-methyl-4-oxopiperidine-1,3-dicarboxylate

: 76508-65-1
(3RS,4SR)-ethyl 1-methoxycarbonyl-4-benzylaminopiperidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / molecular sieve 3A / toluene / 20 h / Heating

2: 78 percent / hydrogen / 5percent Pt-C / ethanol / 72 h / 45003.6 Torr

With 3 A molecular sieve; hydrogen; platinum on activated charcoal; In ethanol; toluene;
DOI:10.3891/acta.chem.scand.34b-0319