Technology Process of Methyl 3-chloro-5-(methoxymethoxy)benzoate
There total 4 articles about Methyl 3-chloro-5-(methoxymethoxy)benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
tetrahydrofuran;
for 3h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: hexamethylphosphoramide / 15 h / 115 - 120 °C
2: 70 percent / acetyl chloride / 15 h / Ambient temperature
3: 93 percent / BBr3 / CH2Cl2 / 3 h / 0 °C
4: 93 percent / NaH / tetrahydrofuran / 3 h / Ambient temperature
With
N,N,N,N,N,N-hexamethylphosphoric triamide; boron tribromide; sodium hydride; acetyl chloride;
In
tetrahydrofuran; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 70 percent / acetyl chloride / 15 h / Ambient temperature
2: 93 percent / BBr3 / CH2Cl2 / 3 h / 0 °C
3: 93 percent / NaH / tetrahydrofuran / 3 h / Ambient temperature
With
boron tribromide; sodium hydride; acetyl chloride;
In
tetrahydrofuran; dichloromethane;
