N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Base Information

Chemical Name:N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide
CAS No.:1312595-11-1
Molecular Formula:C₂₁H₁₈ClN₃O₃S₂
Molecular Weight:459.977
Hs Code.:

Synonyms:N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Suppliers and Price of N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

There total 8 articles about N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1312595-10-0
2-amino-4-{[(3-chlorophenyl)sulfonyl]amino}-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridine-5-carboxylic acid

: 1312595-11-1
N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Guidance literature:: With quinoline; copper; at 200 ℃; for 1h;

Reference yield:

: 586-37-8
1-(3-Methoxyphenyl)ethanone

: 1312595-11-1
N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Guidance literature:: Multi-step reaction with 8 steps

1.1: 1,1,1,3,3,3-hexamethyl-disilazane; acetic acid / 16 h / 70 °C / Inert atmosphere

2.1: sulfur; sodium hydrogencarbonate; water / tetrahydrofuran / 0.75 h / 35 °C / Inert atmosphere

3.1: tin(IV) chloride / toluene / 3.5 h / 20 °C / Reflux

3.2: 20 °C

4.1: N-Bromosuccinimide / dichloromethane / 0.75 h / 20 °C

5.1: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 6 h / 110 °C

6.1: sodium t-butanolate / tetrahydrofuran / 3.75 h / 20 °C

7.1: sodium hydroxide; water / dimethyl sulfoxide / 0.67 h / 150 °C

7.2: 20 °C / pH 6

8.1: copper; quinoline / 1 h / 200 °C

With quinoline; N-Bromosuccinimide; water; tin(IV) chloride; copper; sodium hydrogencarbonate; caesium carbonate; sulfur; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane; sodium hydroxide; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; 1,4-dioxane; dichloromethane; dimethyl sulfoxide; toluene;

Reference yield:

: 86604-43-5
2-(1-(3-methoxyphenyl)ethylidene)malononitrile

: 1312595-11-1
N-{2-amino-6-methyl-3-[3-(methyloxy)phenyl]thieno[2,3-b]pyridin-4-yl}-3-chlorobenzenesulfonamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: sulfur; sodium hydrogencarbonate; water / tetrahydrofuran / 0.75 h / 35 °C / Inert atmosphere

2.1: tin(IV) chloride / toluene / 3.5 h / 20 °C / Reflux

2.2: 20 °C

3.1: N-Bromosuccinimide / dichloromethane / 0.75 h / 20 °C

4.1: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 6 h / 110 °C

5.1: sodium t-butanolate / tetrahydrofuran / 3.75 h / 20 °C

6.1: sodium hydroxide; water / dimethyl sulfoxide / 0.67 h / 150 °C

6.2: 20 °C / pH 6

7.1: copper; quinoline / 1 h / 200 °C

With quinoline; N-Bromosuccinimide; water; tin(IV) chloride; copper; sodium hydrogencarbonate; caesium carbonate; sulfur; sodium hydroxide; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; 1,4-dioxane; dichloromethane; dimethyl sulfoxide; toluene;