[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol

Base Information

Chemical Name:[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol
CAS No.:118237-82-4
Molecular Formula:C₁₁H₁₃N₅O
Molecular Weight:231.257
Hs Code.:

Synonyms:2-Cyclopentene-1-methanol,4-(6-amino-9H-purin-9-yl)-, cis-(?à)-; 2-Cyclopentene-1-methanol, 4-(6-amino-9H-purin-9-yl)-, cis-; NSC614841

Suppliers and Price of [(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol

Chemical Property:

Vapor Pressure:1.64E-11mmHg at 25°C
Boiling Point:516.9°Cat760mmHg
Flash Point:266.4°C
Density:1.61g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol

There total 6 articles about [(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 137836-49-8,137836-50-1
Acetic acid (1R,4S)-4-(6-amino-purin-9-yl)-cyclopent-2-enylmethyl ester

: 118237-82-4,121481-93-4,147332-45-4
(+/-)-cis-9H-9-<4-(hydroxymethyl)-2-cyclopenten-1-yl>adenine

Guidance literature:: With methanol; triethylamine; Heating;
DOI:10.1039/P19910002603

Reference yield:

: 9-((1S,4R)-4-Benzyloxymethyl-cyclopent-2-enyl)-9H-purin-6-ylamine

: 118237-82-4,121481-93-4,147332-45-4
(+/-)-cis-9H-9-<4-(hydroxymethyl)-2-cyclopenten-1-yl>adenine

Guidance literature:: With boron trichloride; In dichloromethane; at -78 - 20 ℃; for 0.583333h;
DOI:10.1021/jo9919759

Reference yield:

: 143643-00-9
(1R,4S)-4-Benzyloxymethyl-cyclopent-2-enol

: 118237-82-4,121481-93-4,147332-45-4
(+/-)-cis-9H-9-<4-(hydroxymethyl)-2-cyclopenten-1-yl>adenine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / CH₂Cl₂ / 0.33 h

2: Pd(PPh₃)4 / dimethylformamide / 1.5 h / 10 °C

3: BCl₃ / CH₂Cl₂ / 0.58 h / -78 - 20 °C

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; boron trichloride; In dichloromethane; N,N-dimethyl-formamide; 1: Condensation / 2: Substitution / 3: debenzylation;
DOI:10.1021/jo9919759