dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine

Base Information

• Chemical Name: dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine
• CAS No.: 959398-22-2
• Molecular Formula: C₁₉H₃₁N₂P
• Molecular Weight: 318.442
• Mol file: 959398-22-2.mol

Synonyms:dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine

Chemical Property of dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine

There total 1 articles about dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

C19H31N2P*BH3 → dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine (959398-22-2)

Guidance literature:

C₁₉H₃₁N₂P*BH₃; With tetrafluoroboric acid dimethyl ether complex; In dichloromethane; at -15 - 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 0.333333h; Further stages.;

DOI:10.1039/b709032c

Reference yield: 42.0%

dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine (959398-22-2) + dichloro(1,5-cyclooctadiene)palladium(II) (12107-56-1) → [dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine] palladium dichloride (959398-25-5)

Guidance literature:

In dichloromethane; (under N2, Schlenk); soln. of Pd-complex added to flask, CH2Cl2 added, stirred, soln. transferred into flask with ligand at -10°C, stirred at room temp. overnight; solvent removed in vacuo, recrystd. from CH2Cl2-Et2O; elem. anal.;

DOI:10.1039/b709032c

Reference yield: 26.0%

dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine (959398-22-2) + dichloro(1,5-cyclooctadiene)palladium(II) (12107-56-1) → bis[dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine]palladium dichloride (959398-27-7)

Guidance literature:

In dichloromethane; (under N2, Schlenk); soln. of Pd-complex added to flask, CH2Cl2 added, stirred, soln. transferred into flask with ligand at -10°C, stirred at 40°C overnight; solvent removed in vacuo, CH2Cl2 layered with Et2O; elem. anal.;

DOI:10.1039/b709032c

Downstream raw materials:

[dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine] palladium dichloride

bis[dicyclohexylphosphinomethyl-methyl-pyridin-2-ylamine]palladium dichloride

C₅H₄N₂CH₃CH₂P(C₆H₁₁)2BH₃