2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

Base Information

Chemical Name:2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile
CAS No.:762172-96-3
Molecular Formula:C₂₂H₁₈FN₅S
Molecular Weight:403.483
Hs Code.:

Synonyms:2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

Suppliers and Price of 2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

There total 1 articles about 2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 762172-93-0
[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]acetonitrile

: 74-88-4
methyl iodide

: 762172-96-3
2-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]-2-methylpropionitrile

Guidance literature:: [2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]acetonitrile; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.0833333h;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 12h; Further stages.;
DOI:10.1016/j.ejmech.2007.09.013