5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-

Base Information

Chemical Name:5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-
CAS No.:84923-01-3
Molecular Formula:C₂₁H₂₆N₄O₂
Molecular Weight:366.463
Hs Code.:
DSSTox Substance ID:DTXSID401005211
Mol file:84923-01-3.mol

Synonyms:BRN 5630430;84923-01-3;5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-;N-(8-Benzyl-3-beta-nortropanyl)-4-ethoxy-5-pyrimidinecarboxamide;5-Pyrimidinecarboxamide, N-(8-benzyl-3-beta-nortropanyl)-4-ethoxy-;DTXSID401005211;LS-134774;N-(8-Benzyl-8-azabicyclo[3.2.1]octan-3-yl)-4-ethoxypyrimidine-5-carboximidic acid

Suppliers and Price of 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-PYRIMIDINECARBOXAMIDE, 4-ETHOXY-N-(8-(PHENYLMETHYL)-8-AZABICYCLO(3.2.1)OCT-3-YL)-, EXO- 95.00%
5MG
$ 505.98

Total 0 raw suppliers

Chemical Property of 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-

Chemical Property:

Vapor Pressure:2.65E-12mmHg at 25°C
Boiling Point:553.7°C at 760 mmHg
Flash Point:288.7°C
PSA：70.84000
Density:1.23g/cm³
LogP:3.31340
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:366.20557608
Heavy Atom Count:27
Complexity:483

Purity/Quality:: 5-PYRIMIDINECARBOXAMIDE, 4-ETHOXY-N-(8-(PHENYLMETHYL)-8-AZABICYCLO(3.2.1)OCT-3-YL)-, EXO- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=NC=NC=C1C(=O)NC2CC3CCC(C2)N3CC4=CC=CC=C4

Technology Process of 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo-

There total 3 articles about 5-Pyrimidinecarboxamide, 4-ethoxy-N-(8-(phenylmethyl)-8-azabicyclo(3.2.1)oct-3-yl)-, exo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 542-05-2
acetonedicarboxylic acid

: 84923-01-3
4-Ethoxy-pyrimidine-5-carboxylic acid ((1R,3S,5S)-8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide

Guidance literature:: Multi-step reaction with 4 steps

2: NH₂OH*HCl / 0.67 h

3: 80 percent / Na / pentan-1-ol / 80 °C / Heating

4: 1.) NEt₃, ethylchloroformate / 1.) DMF, 2 deg C, 0.5 h; 2.) DMF, 12 h, RT

With hydroxylamine hydrochloride; sodium; chloroformic acid ethyl ester; triethylamine; In pentan-1-ol;

Reference yield:

: 532-24-1
tropinone

: 84923-01-3
4-Ethoxy-pyrimidine-5-carboxylic acid ((1R,3S,5S)-8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: NH₂OH*HCl / 0.67 h

2: 80 percent / Na / pentan-1-ol / 80 °C / Heating

3: 1.) NEt₃, ethylchloroformate / 1.) DMF, 2 deg C, 0.5 h; 2.) DMF, 12 h, RT

With hydroxylamine hydrochloride; sodium; chloroformic acid ethyl ester; triethylamine; In pentan-1-ol;

Reference yield:

: 1515-26-0
(1R,5S)-8-Methyl-8-aza-bicyclo[3.2.1]octan-3-one oxime

: 84923-01-3
4-Ethoxy-pyrimidine-5-carboxylic acid ((1R,3S,5S)-8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / Na / pentan-1-ol / 80 °C / Heating

2: 1.) NEt₃, ethylchloroformate / 1.) DMF, 2 deg C, 0.5 h; 2.) DMF, 12 h, RT

With sodium; chloroformic acid ethyl ester; triethylamine; In pentan-1-ol;