(+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester

Base Information

• Chemical Name: (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester
• CAS No.: 108886-28-8
• Molecular Formula: C₁₉H₃₃O₃P
• Molecular Weight: 340.443
• Mol file: 108886-28-8.mol

Synonyms:(+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester

Chemical Property of (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester

There total 8 articles about (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

α-Jonyliden-aethylbromid (67689-04-7) + triethyl phosphite (122-52-1) → (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester (108886-28-8)

Guidance literature:

at 100 ℃; for 1h;

DOI:10.1002/hlca.19860690409

Reference yield:

diethyl [(1E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-1,4-dien-1-yl]phosphonate → (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester (108886-28-8)

Guidance literature:

With sodium t-butanolate; In dimethyl sulfoxide; toluene; at -15 ℃; for 3.5h; Inert atmosphere;

DOI:10.1055/s-0034-1378941

Reference yield:

(3E)-2-methyl-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-enal (58102-02-6) → (+/-)-<3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-yl>phosphonsaeure-diethylester (108886-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / toluene / 1 h / 10 - 15 °C / Inert atmosphere

1.2: 1 h / 10 - 15 °C

2.1: sodium t-butanolate / dimethyl sulfoxide; toluene / 3.5 h / -15 °C / Inert atmosphere

With sodium hydride; sodium t-butanolate; In dimethyl sulfoxide; toluene;

DOI:10.1055/s-0034-1378941

upstream raw materials:

α-Jonyliden-aethylbromid

triethyl phosphite

alpha-ionone

(+/-)-(2E)-3-Methyl-5-(2,6,6-trimethylcyclohex-2-en-1-yl)penta-2,4-dien-1-ol

Downstream raw materials:

epsilon-carotene