propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

Base Information

Chemical Name:propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester
CAS No.:1154062-01-7
Molecular Formula:C₂₃H₂₄F₆O₃
Molecular Weight:462.432
Hs Code.:

Synonyms:propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

Suppliers and Price of propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

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Technology Process of propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

There total 1 articles about propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 916525-74-1
(1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethanol

: 802294-64-0,79-09-4
propionic acid

: 1154062-01-7
propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

Guidance literature:: With dmap; diisopropyl-carbodiimide; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.tetasy.2009.02.004

Reference yield: 48.0%

: 1154062-01-7
propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

: 100-39-0
benzyl bromide

: 2-methyl-3-phenylpropanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester

Guidance literature:: propanoic acid (1R,2S)-2-(2-methylpropoxy)-1,2-bis[2-(trifluoromethyl)phenyl]ethyl ester; With lithium diisopropyl amide; In tetrahydrofuran; at -70 ℃; for 1.5h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; at -70 - 20 ℃; optical yield given as %de; Inert atmosphere;
DOI:10.1016/j.tetasy.2009.02.004