N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

Base Information

Chemical Name:N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine
CAS No.:484644-47-5
Molecular Formula:C₂₀H₂₂ClN₃
Molecular Weight:339.868
Hs Code.:

Synonyms:N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

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Technology Process of N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

There total 2 articles about N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1824-81-3
2-Amino-6-methylpyridine

: 931-53-3
Cyclohexyl isocyanide

: 104-88-1
4-chlorobenzaldehyde

: 484644-47-5
N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

Guidance literature:: With bismuth(III) chloride; In neat (no solvent); at 110 ℃;
DOI:10.1055/s-0032-1318221

Reference yield:

: 873-76-7
para-Chlorobenzyl alcohol

: 484644-47-5
N-[2-(4-chlorophenyl)-5-methylimidazo[1,2-a]pyridin-3-yl]-N-cyclohexylamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / toluene / 5 h / 80 °C / Green chemistry

2: toluene / 3 h / 80 °C

With potassium hydroxide; In toluene;
DOI:10.1007/s13738-020-02102-x