ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate

Base Information

• Chemical Name: ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate
• CAS No.: 1350915-96-6
• Molecular Formula: C₂₄H₂₃F₄NO₃S₂
• Molecular Weight: 513.577
• Mol file: 1350915-96-6.mol

Synonyms:ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate

Chemical Property of ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate

There total 1 articles about ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl bromofluoroacetate (401-55-8) + 2-ethyl-4-{[4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl]methylthio}phenol (1268500-80-6) → ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate (1350915-96-6)

Guidance literature:

With caesium carbonate; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2011.10.020

Reference yield: 67.0%

ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate (1350915-96-6) → 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)acetic acid (1350915-99-9)

Guidance literature:

ethyl 2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)-acetate; With lithium hydroxide; In tetrahydrofuran; water; at 0 ℃;

With hydrogenchloride; In tetrahydrofuran; water;

DOI:10.1016/j.bmc.2011.10.020

upstream raw materials:

ethyl bromofluoroacetate

2-ethyl-4-{[4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl]methylthio}phenol

Downstream raw materials:

2-fluoro-2-(2-ethyl-4-((4-methyl-2-(4-trifluoromethylphenyl)thiazol-5-yl)methylthio)phenoxy)acetic acid