tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate
CAS No.:1454284-94-6
Molecular Formula:C₂₅H₃₀FN₅O₅S
Molecular Weight:531.608
Hs Code.:

Synonyms:tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

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Chemical Property of tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

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Technology Process of tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

There total 4 articles about tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 934536-10-4,577691-56-6
(trans)-tert-butyl 4-amino-3-fluoropiperidine-1-carboxylate

: 1453176-75-4
4-{[(imidazo[1,2-a]pyridine-6-carbonyl)-amino]-methyl}-benzenesulfonyl chloride

: 1454284-94-6
tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 1453176-74-3
imidazo[1.2-a]pyridine-6-carboxylic acid benzylamide

: 1454284-94-6
tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: chlorosulfonic acid / 2.5 h / 20 °C / Cooling with ice

2: triethylamine / dichloromethane / 24 h / 20 °C

With chlorosulfonic acid; triethylamine; In dichloromethane;

Reference yield:

: 100-46-9
benzylamine

: 1454284-94-6
tert-butyl 3-fluoro-4-[[4-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]phenyl]sulfonylamino]piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate / dichloromethane / 24 h / 20 °C

2: chlorosulfonic acid / 2.5 h / 20 °C / Cooling with ice

3: triethylamine / dichloromethane / 24 h / 20 °C

With chlorosulfonic acid; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In dichloromethane;