Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Base Information

Chemical Name:Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester
CAS No.:653568-39-9
Molecular Formula:C₂₂H₃₂O₆Si
Molecular Weight:420.578
Hs Code.:

Synonyms:Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Suppliers and Price of Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

There total 9 articles about Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 333-27-7
methyl trifluoromethanesulfonate

: 653568-38-8
Benzoic acid (R)-{(2S,5S,6S)-2-hydroxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methoxycarbonyl-methyl ester

: 653568-39-9
Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; 1,2-dimethoxyethane; at -70 ℃; for 0.75h;
DOI:10.1021/ja038787r

Reference yield:

: 3724-55-8
methyl but-3-enoate

: 653568-39-9
Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 63 percent / CpRu(CH₃CN)3PF₆ / acetone / 3.5 h / 20 °C

2: 100 percent / triethylamine / CH₂Cl₂ / 0.33 h / -78 °C

3: 96 percent / NMO; OsO₄ / acetone; H₂O / 60 h / 2 °C

4: 70 percent / DMAP; Et₃N / CH₂Cl₂ / -78 - -45 °C

5: Dess-Martin periodinane; Na₂CO₃ / CH₂Cl₂ / 0.67 h / 20 °C

6: CSA / methanol / 3 h / 20 °C

7: 103 mg / LHMDS / 1,2-dimethoxy-ethane; tetrahydrofuran / 0.75 h / -70 °C

With dmap; osmium(VIII) oxide; N-methyl-2-indolinone; cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; camphor-10-sulfonic acid; sodium carbonate; Dess-Martin periodane; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; acetone;
DOI:10.1021/ja038787r

Reference yield:

: 1066-54-2
trimethylsilylacetylene

: 653568-39-9
Benzoic acid (R)-methoxycarbonyl-{(2S,5S,6S)-2-methoxy-5,6-dimethyl-4-[1-trimethylsilanyl-meth-(Z)-ylidene]-tetrahydro-pyran-2-yl}-methyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 63 percent / CpRu(CH₃CN)3PF₆ / acetone / 3.5 h / 20 °C

2: 100 percent / triethylamine / CH₂Cl₂ / 0.33 h / -78 °C

3: 96 percent / NMO; OsO₄ / acetone; H₂O / 60 h / 2 °C

4: 70 percent / DMAP; Et₃N / CH₂Cl₂ / -78 - -45 °C

5: Dess-Martin periodinane; Na₂CO₃ / CH₂Cl₂ / 0.67 h / 20 °C

6: CSA / methanol / 3 h / 20 °C

7: 103 mg / LHMDS / 1,2-dimethoxy-ethane; tetrahydrofuran / 0.75 h / -70 °C

With dmap; osmium(VIII) oxide; N-methyl-2-indolinone; cyclopentadienylruthenium(II) trisacetonitrile hexafluorophosphate; camphor-10-sulfonic acid; sodium carbonate; Dess-Martin periodane; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; acetone;
DOI:10.1021/ja038787r