4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine

Base Information

• Chemical Name: 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine
• CAS No.: 556809-45-1
• Molecular Formula: C₂₇H₂₉NO₃
• Molecular Weight: 415.532
• Mol file: 556809-45-1.mol

Synonyms:4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine

Chemical Property of 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine

There total 5 articles about 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

9-{3-[3-(2,2-dimethoxyethyl)-4-nitrophenoxy]propyl}anthracene (556809-44-0) → 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine (556809-45-1)

Guidance literature:

With copper acetylacetonate; sodium tetrahydroborate; In methanol; dichloromethane; isopropyl alcohol; for 0.5h; Heating;

DOI:10.1021/jo034219i

Reference yield:

3-methyl-4-nitrophenol (2581-34-2,910311-23-8) → 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine (556809-45-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 99 percent / K₂CO₃ / dimethylformamide / 2 h / 90 °C

2.1: dimethylformamide / 16 h / Heating

2.2: 73 percent / aqueous HCl / diethyl ether / 2 h / Heating

3.1: 100 percent / p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h / Heating

4.1: 74 percent / copper acetylacetonate; sodium borohydride / CH₂Cl₂; propan-2-ol; methanol / 0.5 h / Heating

With copper acetylacetonate; sodium tetrahydroborate; potassium carbonate; toluene-4-sulfonic acid; In methanol; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1021/jo034219i

Reference yield:

9-(3-iodopropyl)anthracene (556809-41-7) → 4-(3-anthracen-9-ylpropoxy)-2-(2,2-dimethoxyethyl)phenylamine (556809-45-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 99 percent / K₂CO₃ / dimethylformamide / 2 h / 90 °C

2.1: dimethylformamide / 16 h / Heating

2.2: 73 percent / aqueous HCl / diethyl ether / 2 h / Heating

3.1: 100 percent / p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h / Heating

4.1: 74 percent / copper acetylacetonate; sodium borohydride / CH₂Cl₂; propan-2-ol; methanol / 0.5 h / Heating

With copper acetylacetonate; sodium tetrahydroborate; potassium carbonate; toluene-4-sulfonic acid; In methanol; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1021/jo034219i

upstream raw materials:

9-{3-[3-(2,2-dimethoxyethyl)-4-nitrophenoxy]propyl}anthracene

3-methyl-4-nitrophenol

9-(3-iodopropyl)anthracene

9-[3-(3-methyl-4-nitrophenoxy)propyl]anthracene

Downstream raw materials:

N-[4-(3-anthracen-9-ylpropoxy)-2-(2,2-methoxyethyl)phenyl]-4-bromobenzamide