Phorbol

Base Information Edit

Chemical Name:Phorbol
CAS No.:17673-25-5
Deprecated CAS:110675-79-1
Molecular Formula:C20H28 O6
Molecular Weight:364.439
Hs Code.:29062990
European Community (EC) Number:634-015-4,636-778-9
UN Number:2811
UNII:XUZ76S9127
DSSTox Substance ID:DTXSID2021155
Nikkaji Number:J9.694F
Wikipedia:Phorbol
Wikidata:Q2705359
Metabolomics Workbench ID:28629
ChEMBL ID:CHEMBL124518
Mol file:17673-25-5.mol

Synonyms:4-alpha-phorbol;4alpha-phorbol;beta-phorbol;isophorbol;phorbol;phorbol, (1aR-(1aalpha,1bbeta,4aalpha,7aalpha,7balpha,8alpha,9beta,9bbeta))-isomer

Suppliers and Price of Phorbol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Phorbol
50mg
$ 675.00

TCI Chemical
Phorbol
25MG
$ 384.00

TCI Chemical
Phorbol
5MG
$ 128.00

Medical Isotopes, Inc.
Phorbol
50 mg
$ 2440.00

Crysdot
Phorbol 97%
5mg
$ 196.00

Chem-Impex
Phorbol,≥98%(HPLC) ≥98%(HPLC)
5MG
$ 125.80

Cayman Chemical
Phorbol ≥98%
1mg
$ 59.00

Cayman Chemical
Phorbol ≥98%
5mg
$ 266.00

Biorbyt Ltd
Phorbol
10 mg
$ 472.60

Biorbyt Ltd
Phorbol >99% pure
300 mg
$ 902.70

Total 40 raw suppliers

Chemical Property of Phorbol Edit

Chemical Property:

Vapor Pressure:1.83E-15mmHg at 25°C
Melting Point:162-163° and 233-234°; mp 249-250°
Refractive Index:1.4450 (estimate)
Boiling Point:572 °C at 760 mmHg
PKA:11.36±0.70(Predicted)
Flash Point:313.8 °C
PSA：118.22000
Density:1.415 g/cm³
LogP:-0.06990
Storage Temp.:−20°C
Water Solubility.:Soluble in water
XLogP3:-0.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:364.18858861
Heavy Atom Count:26
Complexity:753
Transport DOT Label:Poison

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phorbol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T+
Statements: 26/27/28-36/37/38
Safety Statements: 26-27-36/37/39-45-28

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Biological Agents -> Plant Toxins
Canonical SMILES:CC1C(C2(C(C2(C)C)C3C1(C4C=C(C(=O)C4(CC(=C3)CO)O)C)O)O)O
Isomeric SMILES:C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)CO)O)C)O)O)O
Description Phorbol is a diterpene originally isolated from croton oil. It is used as a starting material for the semisynthesis of various phorbol diesters, which are structurally analogous to diacylglycerol and activate PKC isoforms by associating with their C1 domains.
Uses Phorbol is a plant-derived diterpene that exhibits various biological activities such as its role as tumor promoters through the activation of protein kinase C.

Technology Process of Phorbol

There total 64 articles about Phorbol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%