Technology Process of tert-butyl ((1R)-2-{[4-formyl-1-(phenylsulfonyl)-1H-indol-5-yl]oxy}-1-methylethyl)carbamate
There total 5 articles about tert-butyl ((1R)-2-{[4-formyl-1-(phenylsulfonyl)-1H-indol-5-yl]oxy}-1-methylethyl)carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diamide; triphenylphosphine;
In
dichloromethane;
at 20 - 45 ℃;
for 96h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
2: ammonium formate / palladium 10% on activated carbon / tetrahydrofuran; methanol / 20 °C
3: potassium hydroxide / methanol; water / 40 °C
4: manganese(IV) oxide / dichloromethane / 2 h / 20 °C
5: diamide; triphenylphosphine / dichloromethane / 96 h / 20 - 45 °C
With
manganese(IV) oxide; potassium hydroxide; sodium hydroxide; diamide; ammonium formate; tetra(n-butyl)ammonium hydrogensulfate; triphenylphosphine;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
2: ammonium formate / palladium 10% on activated carbon / tetrahydrofuran; methanol / 20 °C
3: potassium hydroxide / methanol; water / 40 °C
4: manganese(IV) oxide / dichloromethane / 2 h / 20 °C
5: diamide; triphenylphosphine / dichloromethane / 96 h / 20 - 45 °C
With
manganese(IV) oxide; potassium hydroxide; sodium hydroxide; diamide; ammonium formate; tetra(n-butyl)ammonium hydrogensulfate; triphenylphosphine;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; dichloromethane; water;