Technology Process of 5-benzyloxypentyl-2,3:5,6-di-O-isopropylidene-4-methoxymethyl-D-galactoside
There total 9 articles about 5-benzyloxypentyl-2,3:5,6-di-O-isopropylidene-4-methoxymethyl-D-galactoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,3:5,6-diisopropylidene-4-methoxymethyl-galactitol;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 1h;
1-(benzyloxy)-5-bromopentane;
In
N,N-dimethyl-formamide;
at 0 - 80 ℃;
for 55h;
DOI:10.1021/jm030464i
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 75 percent / Ag2O / CH2Cl2
2.1: 55.2 percent / imidazole; PPh3; CBr4 / 0 - 20 °C
3.1: NaH / dimethylformamide / 1 h / 0 °C
3.2: 53.6 percent / dimethylformamide / 55 h / 0 - 80 °C
With
1H-imidazole; carbon tetrabromide; sodium hydride; triphenylphosphine; silver(l) oxide;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm030464i
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 75 percent / conc. HCl / 18 h / 0 - 4 °C
2.1: 58 percent / PTSA / acetone / 2 h
3.1: 79 percent / (iPr)2EtN / CH2Cl2 / 6 h / 20 °C
4.1: aq. HgCl2; CdCO3 / acetone / 2 h / 50 °C
5.1: 60 percent / NaBH4 / methanol / 4 h / 0 - 20 °C
6.1: NaH / dimethylformamide / 1 h / 0 °C
6.2: 53.6 percent / dimethylformamide / 55 h / 0 - 80 °C
With
hydrogenchloride; sodium tetrahydroborate; cadmium(II) carbonate; sodium hydride; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; mercury dichloride;
In
methanol; dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm030464i
