(E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime

Base Information

• Chemical Name: (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime
• CAS No.: 1343411-26-6
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.299
• Mol file: 1343411-26-6.mol

Synonyms:(E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime

Chemical Property of (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime

There total 5 articles about (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

(E)-1-(4-methoxy-2,5-dimethylphenyl)ethanone-propyloxime (1343411-25-5) → (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime (1343411-26-6)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃;

Reference yield:

1-(4-methoxy-2,5-dimethylphenyl)ethanone (104174-28-9) → (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime (1343411-26-6)

Guidance literature:

Multi-step reaction with 3 steps

1: hydroxylamine hydrochloride / methanol / 3 h / 20 °C / Molecular sieve

2: caesium carbonate / acetonitrile / 3 h / 20 °C

3: boron tribromide / dichloromethane / 20 °C

With hydroxylamine hydrochloride; boron tribromide; caesium carbonate; In methanol; dichloromethane; acetonitrile;

Reference yield:

(E)-1-(4-methoxy-2,5-dimethylphenyl)ethanone oxime (1343411-23-3) → (E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime (1343411-26-6)

Guidance literature:

Multi-step reaction with 2 steps

1: caesium carbonate / acetonitrile / 3 h / 20 °C

2: boron tribromide / dichloromethane / 20 °C

With boron tribromide; caesium carbonate; In dichloromethane; acetonitrile;

upstream raw materials:

2,5-dimethyl-p-anisaldehyde

1-(4-methoxy-2,5-dimethylphenyl)ethanol

1-(4-methoxy-2,5-dimethylphenyl)ethanone

(E)-1-(4-methoxy-2,5-dimethylphenyl)ethanone oxime

Downstream raw materials:

(E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate