(E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate

Base Information

• Chemical Name: (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate
• CAS No.: 159918-55-5
• Molecular Formula: C₂₅H₃₁NO₅
• Molecular Weight: 425.525
• Mol file: 159918-55-5.mol

Synonyms:(E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate

Chemical Property of (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate

There total 6 articles about (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

(E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime (1343411-26-6) + methyl (E)-2-(2-bromomethylphenyl)-3-methoxyacrylate (117428-49-6) → (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate (159918-55-5)

Guidance literature:

With caesium carbonate; In acetonitrile; at 20 ℃; for 3h;

Reference yield:

1-(4-methoxy-2,5-dimethylphenyl)ethanone (104174-28-9) → (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate (159918-55-5)

Guidance literature:

Multi-step reaction with 4 steps

1: hydroxylamine hydrochloride / methanol / 3 h / 20 °C / Molecular sieve

2: caesium carbonate / acetonitrile / 3 h / 20 °C

3: boron tribromide / dichloromethane / 20 °C

4: caesium carbonate / acetonitrile / 3 h / 20 °C

With hydroxylamine hydrochloride; boron tribromide; caesium carbonate; In methanol; dichloromethane; acetonitrile;

Reference yield:

(E)-1-(4-methoxy-2,5-dimethylphenyl)ethanone oxime (1343411-23-3) → (E)-methyl 2-(2-((2,5-dimethyl-4-((E)-1-(propoxyimino)ethyl)phenoxy)methyl)-phenyl)-3-methoxyacrylate (159918-55-5)

Guidance literature:

Multi-step reaction with 3 steps

1: caesium carbonate / acetonitrile / 3 h / 20 °C

2: boron tribromide / dichloromethane / 20 °C

3: caesium carbonate / acetonitrile / 3 h / 20 °C

With boron tribromide; caesium carbonate; In dichloromethane; acetonitrile;

upstream raw materials:

(E)-1-(4-hydroxy-2,5-dimethylphenyl)ethanone propyloxime

methyl (E)-2-(2-bromomethylphenyl)-3-methoxyacrylate

2,5-dimethyl-p-anisaldehyde

1-(4-methoxy-2,5-dimethylphenyl)ethanol