{(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester

Base Information

• Chemical Name: {(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester
• CAS No.: 129422-73-7
• Molecular Formula: C₁₄H₂₆NO₃P
• Molecular Weight: 287.339
• Mol file: 129422-73-7.mol

Synonyms:{(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester

Chemical Property of {(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester

There total 9 articles about {(E)-4-[(E)-Cyclohexylimino]-but-2-enyl}-phosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-(4-Oxo-2-butenyl)phosphonsaeure-diethylester (110905-37-8) + cyclohexylamine (108-91-8,157973-60-9) → (5-aza-5-cyclohexylpenta-2,4-dienyl)diethoxyphosphin-1-one (129422-73-7)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/jo0105383

Reference yield:

diethoxy(4-hydroxybut-2-enyl)phosphino-1-one (915100-96-8) → (5-aza-5-cyclohexylpenta-2,4-dienyl)diethoxyphosphin-1-one (129422-73-7)

Guidance literature:

Multi-step reaction with 3 steps

1: CrO₃ / aq. H₂SO₄ / 0.5 h / 0 - 20 °C

2: 380 mg / aq. H₂SO₄ / acetone / 60 °C

3: 100 percent / tetrahydrofuran / 1 h / 20 °C

With chromium(VI) oxide; sulfuric acid; In tetrahydrofuran; sulfuric acid; acetone;

DOI:10.1021/jo0105383

Reference yield:

4-oxo-2-butenophosphonic acid ethyl ester (110905-37-8,118430-38-9) → (5-aza-5-cyclohexylpenta-2,4-dienyl)diethoxyphosphin-1-one (129422-73-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 380 mg / aq. H₂SO₄ / acetone / 60 °C

2: 100 percent / tetrahydrofuran / 1 h / 20 °C

With sulfuric acid; In tetrahydrofuran; acetone;

DOI:10.1021/jo0105383

upstream raw materials:

(E)-(4-Oxo-2-butenyl)phosphonsaeure-diethylester

cyclohexylamine

diethoxy(4-hydroxybut-2-enyl)phosphino-1-one

diethyl (4-acetoxy-2-buten-1-yl)phosphonate

Downstream raw materials:

trans,trans-2,4-dodecadienal

(E)-5-cyclohexylidene-2,4-pentadienal

(Z)-4-Cyclohexylidene-but-2-enal

(2E,4E)-5-(4-methoxyphenyl)penta-2,4-dienal