Boc-Aminooxy-PEG2-amine

Base Information

Chemical Name:Boc-Aminooxy-PEG2-amine
CAS No.:252378-69-1
Molecular Formula:C₁₁H₂₄N₂O₅
Molecular Weight:264.322
Hs Code.:
Mol file:252378-69-1.mol

Synonyms:C₁₁H₂₄N₂O₅

Suppliers and Price of Boc-Aminooxy-PEG2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
t-Boc-Aminooxy-PEG2-amine 98%
1 G
$ 1400.00

BroadPharm
t-Boc-Aminooxy-PEG2-amine 98%
500 MG
$ 750.00

BroadPharm
t-Boc-Aminooxy-PEG2-amine 98%
250 MG
$ 480.00

BroadPharm
t-Boc-Aminooxy-PEG2-amine 98%
100 MG
$ 280.00

Total 7 raw suppliers

Chemical Property of Boc-Aminooxy-PEG2-amine

Chemical Property:

PKA:8.74±0.10(Predicted)
Density:1.077±0.06 g/cm3(Predicted)
Solubility.:Soluble in Water, DMSO, DMF, DCM

Purity/Quality:

99%, ^*data from raw suppliers

t-Boc-Aminooxy-PEG2-amine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description t-Boc-Aminooxy-PEG2-amine contains a Boc-protected aminooxy group and a free amino(NH2) group. Amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc- aminooxy can be deprotected under mild acidic conditions and then reacts with an aldehyde to form a linkage.

Technology Process of Boc-Aminooxy-PEG2-amine

There total 1 articles about Boc-Aminooxy-PEG2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86520-52-7
2-[2-(2-azidoethoxy)ethoxy]ethanol

: 252378-69-1
C₁₁H₂₄N₂O₅

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; carbon tetrabromide / dichloromethane / 13 h / 0 - 20 °C / Inert atmosphere

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 13 h / 60 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / methanol / 3 h

With carbon tetrabromide; palladium 10% on activated carbon; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In methanol; dichloromethane; acetonitrile;

Reference yield: 85.0%

: 252378-69-1
C₁₁H₂₄N₂O₅

: C₂₇H₄₄N₂O₁₁

: C₃₈H₆₆N₄O₁₅

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 14h; Inert atmosphere;

Reference yield: 84.0%

: 252378-69-1
C₁₁H₂₄N₂O₅

: C₂₂H₂₆O₁₃

: C₃₃H₄₈N₂O₁₇

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 12h; Inert atmosphere;