C₂₀H₂₅NO₃

Base Information

• Chemical Name: C₂₀H₂₅NO₃
• CAS No.: 1221563-15-0
• Molecular Formula: C₂₀H₂₅NO₃
• Molecular Weight: 327.423
• Mol file: 1221563-15-0.mol

Synonyms:C₂₀H₂₅NO₃

Chemical Property of C₂₀H₂₅NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₅NO₃

There total 6 articles about C₂₀H₂₅NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-(2,6-diethyl-4-methylphenyl)-3-hydroxy-3a,4,6,6a-tetrahydropentalene-1,5-dione + N-methylhydroxyamine hydrochloride (4229-44-1) → C20H25NO3 (1221563-15-0)

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃; for 6h;

Reference yield:

C22H30O5 → C20H25NO3 (1221563-15-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: water; potassium hydroxide / 24 h / Reflux

1.2: 1 h / 20 °C / pH 2

2.1: potassium carbonate / acetone / 5 h / Reflux

3.1: potassium tert-butylate / N,N-dimethyl-formamide / 2 h / 50 °C

3.2: pH 3

4.1: sodium periodate; osmium(VIII) oxide; water / ethyl acetate; tert-butyl alcohol / 2.17 h / 20 °C

5.1: triethylamine / acetonitrile / 6 h / 20 °C

With sodium periodate; osmium(VIII) oxide; potassium tert-butylate; water; potassium carbonate; triethylamine; potassium hydroxide; In ethyl acetate; N,N-dimethyl-formamide; acetone; acetonitrile; tert-butyl alcohol;

Reference yield:

2-(2,6-diethyl-4-methylphenyl)-3-hydroxy-5-methylidene-4,5,6,6a-tetrahydropentalen-1(3aH)-one → C20H25NO3 (1221563-15-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium periodate; osmium(VIII) oxide; water / ethyl acetate; tert-butyl alcohol / 2.17 h / 20 °C

2: triethylamine / acetonitrile / 6 h / 20 °C

With sodium periodate; osmium(VIII) oxide; water; triethylamine; In ethyl acetate; acetonitrile; tert-butyl alcohol;

upstream raw materials:

N-methylhydroxyamine hydrochloride

(2,6-diethyl-4-methylphenyl)acetic acid methyl ester