(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

Base Information

Chemical Name:(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide
CAS No.:1404054-70-1
Molecular Formula:C₂₆H₂₇F₂N₂O₂*I
Molecular Weight:564.414
Hs Code.:

Synonyms:(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

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Chemical Property of (3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

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Technology Process of (3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

There total 4 articles about (3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1404054-69-8
(R)-bis(3-fluorophenyl)methyl 1-benzylpyrrolidin-3-ylcarbamate

: 74-88-4
methyl iodide

: 1404054-70-1
(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

Guidance literature:: In ethyl acetate; at 20 ℃;

Reference yield:

: 114715-39-8
(R)-1-benzyl-3-aminopyrrolidine

: 1404054-70-1
(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

Guidance literature:: Multi-step reaction with 3 steps

1.1: N,N-dimethyl-formamide / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 0 - 20 °C

2.2: 20 °C

3.1: ethyl acetate / 20 °C

With sodium hydride; In ethyl acetate; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 383888-08-2
C₁₅H₁₈N₄O

: 1404054-70-1
(3R)-1-benzyl-3-((bis(3-fluorophenyl)methoxy)-carbonylamino)-1-methylpyrrolidinium iodide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 0 - 20 °C

1.2: 20 °C

2.1: ethyl acetate / 20 °C

With sodium hydride; In ethyl acetate; N,N-dimethyl-formamide; mineral oil;