(Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene

Base Information

• Chemical Name: (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene
• CAS No.: 216656-99-4
• Molecular Formula: C₂₅H₂₁ClO₃
• Molecular Weight: 404.893
• Mol file: 216656-99-4.mol

Synonyms:(Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene

Chemical Property of (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene

There total 3 articles about (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(1-chloro-7-methoxyphenanthrylmethyl)triphenylphosphonium bromide + 2,3-dimethyoxybenzaldehyde (86-51-1) → (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene (216656-99-4)

Guidance literature:

With sodium hydroxide; 18-crown-6 ether; In dichloromethane;

DOI:10.1021/jo980416j

Reference yield:

1-chloro-2-methyl-7-methoxyphenanthrene (216656-97-2) → (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene (216656-99-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / N-bromosuccinimide; benzoyl peroxide / CCl₄ / 16 h / Heating

2: 91 percent / toluene / Heating

3: 92 percent / 18-crown-6; aq. NaOH / CH₂Cl₂

With sodium hydroxide; N-Bromosuccinimide; 18-crown-6 ether; dibenzoyl peroxide; In tetrachloromethane; dichloromethane; toluene; 1: Bromination / 2: Alkylation / 3: Wittig reaction;

DOI:10.1021/jo980416j

Reference yield:

2-bromomethyl-1-chloro-7-methoxyphenanthrene (216656-98-3) → (Z)-1-(1-chloro-7-methoxy-2-phenanthryl)-2-(2',3'-dimethoxyphenyl)ethene (216656-99-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / toluene / Heating

2: 92 percent / 18-crown-6; aq. NaOH / CH₂Cl₂

With sodium hydroxide; 18-crown-6 ether; In dichloromethane; toluene; 1: Alkylation / 2: Wittig reaction;

DOI:10.1021/jo980416j

upstream raw materials:

2,3-dimethyoxybenzaldehyde

1-chloro-2-methyl-7-methoxyphenanthrene

2-bromomethyl-1-chloro-7-methoxyphenanthrene