methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Base Information

Chemical Name:methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate
CAS No.:256488-01-4
Molecular Formula:C₁₂H₁₉NO₄
Molecular Weight:241.287
Hs Code.:

Synonyms:methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Suppliers and Price of methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

There total 5 articles about methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40216-83-9
L-4-hydroxyproline methyl ester hydrochloride

: 84348-39-0
(S)-1-tert-butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate

: 256488-01-4
methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine

2: sodium periodate; ruthenium trichloride

With ruthenium trichloride; sodium periodate; triethylamine; 3: Wittig reaction;
DOI:10.1016/j.tetlet.2012.05.020

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 84348-39-0
(S)-1-tert-butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate

: 256488-01-4
methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine

2: sodium periodate; ruthenium trichloride

With ruthenium trichloride; sodium periodate; triethylamine; 3: Wittig reaction;
DOI:10.1016/j.tetlet.2012.05.020

Reference yield:

: 74844-91-0
1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate

: 84348-39-0
(S)-1-tert-butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate

: 256488-01-4
methyl 1N-tert-butoxycarbonyl-4-exomethylene-pyrrolidine-(2R)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium periodate; ruthenium trichloride

With ruthenium trichloride; sodium periodate; 2: Wittig reaction;
DOI:10.1016/j.tetlet.2012.05.020