N-(3-bromophenyl)benzenecarbothioamide

Base Information

• Chemical Name: N-(3-bromophenyl)benzenecarbothioamide
• CAS No.: 108752-45-0
• Molecular Formula: C₁₃H₁₀BrNS
• Molecular Weight: 292.199
• Mol file: 108752-45-0.mol

Synonyms:N-(3-bromophenyl)benzothioamide

Chemical Property of N-(3-bromophenyl)benzenecarbothioamide

Chemical Property:

Purity/Quality:

N-(3-BROMOPHENYL)BENZENECARBOTHIOAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3-bromophenyl)benzenecarbothioamide

There total 4 articles about N-(3-bromophenyl)benzenecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

phenylacetic acid (103-82-2) + m-nitrobromobenzene (585-79-5) → N-(3-bromophenyl)benzothioamide (108752-45-0)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; sulfur; In neat (no solvent); at 120 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c9ob01751h

Reference yield: 52.0%

benzyl thiosulphate (6313-36-6) + m-Bromoaniline (591-19-5) → N-(3-bromophenyl)benzothioamide (108752-45-0)

Guidance literature:

With 1H-imidazole; sodium carbonate; dimethyl sulfoxide; at 135 ℃; for 48h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c9ob00336c

Reference yield:

m-Bromoaniline (591-19-5) → N-(3-bromophenyl)benzothioamide (108752-45-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3 h / 20 °C

2: Lawessons reagent / toluene / 2 h / Reflux; Inert atmosphere

With Lawessons reagent; triethylamine; In dichloromethane; toluene;

DOI:10.1021/acs.orglett.8b03679

upstream raw materials:

m-Bromoaniline

benzoyl chloride

benzyl thiosulphate

phenylacetic acid

Downstream raw materials:

5-bromo-2-phenylbenzo[d]thiazole

N-(3-bromophenyl)benzamide

7-bromo-2-phenylbenzo[d]thiazole