(E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene

Base Information

• Chemical Name: (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene
• CAS No.: 1614262-44-0
• Molecular Formula: C₁₅H₁₂Cl₂O₂
• Molecular Weight: 295.165
• Mol file: 1614262-44-0.mol

Synonyms:(E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene

Chemical Property of (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene

There total 2 articles about (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-chloro-4-(4-chlorophenoxy)benzaldehyde + methoxymethyltriphenylphosphonium bromide (33670-32-5) → (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene (1614262-44-0)

Guidance literature:

methoxymethyltriphenylphosphonium bromide; With lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h;

2-chloro-4-(4-chlorophenoxy)benzaldehyde; In tetrahydrofuran;

Reference yield: 88.0%

2-chloro-4-(4-chlorophenoxy)benzaldehyde + (methoxymethyl)triphenylphosphonium chloride (4009-98-7) → (E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene (1614262-44-0)

Guidance literature:

(methoxymethyl)triphenylphosphonium chloride; With potassium tert-butylate; In tetrahydrofuran; for 0.5h;

2-chloro-4-(4-chlorophenoxy)benzaldehyde; In tetrahydrofuran;

Reference yield: 73.0%

(E)-2-chloro-4-(4-chlorophenoxy)-1-(2-methoxyvinyl)benzene (1614262-44-0) → 2-(2-chloro-4-(4-chlorophenoxy)phenyl)acetaldehyde (1614262-45-1)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 4h;

upstream raw materials:

methoxymethyltriphenylphosphonium bromide

(methoxymethyl)triphenylphosphonium chloride

Downstream raw materials:

2-(2-chloro-4-(4-chlorophenoxy)phenyl)acetaldehyde

2-(2-chloro-4-(4-chlorophenoxy)phenyl)acetic acid

tert-butyl 2-(2-chloro-4-(4-chlorophenoxy)phenyl)acetate

tert-butyl 2-(2-chloro-4-(4-chlorophenoxy)phenyl)-3-(1-chlorocyclopropyl)-3-oxopropanoate