Technology Process of benzyl (7-benzyloxy-2-oxindolin-3-yl)glyoxylate
There total 9 articles about benzyl (7-benzyloxy-2-oxindolin-3-yl)glyoxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
dibenzyl oxalate;
With
sodium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
Inert atmosphere;
7-benzyloxy-2-indolinone;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; water;
pH=2;
DOI:10.1271/bbb.100124
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetic acid; zinc / 4 h / 110 °C / Inert atmosphere
2.1: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
2.3: pH 2
With
acetic acid; sodium hydroxide; zinc;
In
tetrahydrofuran;
DOI:10.1271/bbb.100124
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydroxide / ethanol; water / 2.5 h / 20 °C / Inert atmosphere
1.2: pH 3
2.1: dihydrogen peroxide; sodium hydroxide / 1,4-dioxane / 1 h / 20 °C / Inert atmosphere
2.2: pH 3
3.1: acetic acid; zinc / 4 h / 110 °C / Inert atmosphere
4.1: sodium hydroxide / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
4.2: 20 °C / Inert atmosphere
4.3: pH 2
With
dihydrogen peroxide; acetic acid; sodium hydroxide; zinc;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1271/bbb.100124
