1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

Base Information

Chemical Name:1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide
CAS No.:1193523-61-3
Molecular Formula:C₁₈H₁₈N₂O₂
Molecular Weight:294.353
Hs Code.:

Synonyms:1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

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Technology Process of 1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

There total 1 articles about 1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1-methyl-1H-pyrrole-2-carboxylic acid methylprop-2-ynylamide

: 13329-40-3
4-Iodoacetophenone

: 1193523-61-3
1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; In tetrahydrofuran; at 60 ℃; for 20h; Inert atmosphere;
DOI:10.1002/anie.200902937

Reference yield: 58.0%

: 1193523-61-3
1-methyl-1H-pyrrole-2-carboxylic acid [3-(4-acetylphenyl)prop-2-ynyl]methylamide

: 1193523-72-6
8-(4-acetylphenyl)-1,5-dimethyl-5,6-dihydro-1H-pyrrolo[3,2-c]azepin-4-one

Guidance literature:: With dihydrogen hexachloroplatinate(IV) hexahydrate; In toluene; at 120 ℃; for 20h; Inert atmosphere;
DOI:10.1002/anie.200902937