Technology Process of 5-azido-6-O-benzoyl-3-O-benzyl-5-deoxy-2,4-O-isopropylidene-L-iditol
There total 7 articles about 5-azido-6-O-benzoyl-3-O-benzyl-5-deoxy-2,4-O-isopropylidene-L-iditol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 7 steps
1: pyridine / 1,2-dichloro-ethane / 1 h / 0 °C
2: sodium azide / dimethylformamide / 1 h / 70 °C
3: 93 percent / 1 M aqu. sulfuric acid / dioxane / 5 h / 80 °C
4: 81 percent / sodium borohydride / 1,2-dimethoxy-ethane / 1 h / 0 °C
5: 90 percent / pyridine / 1,2-dichloro-ethane / 17 h / 37 °C
6: 99 percent / pyridinium p-toluenesulfonate / 1,2-dichloro-ethane / 2 h / 60 °C
7: 87 percent / tetrabutylammonium fluoride / various solvent(s) / 1 h / 0 °C
With
pyridine; sodium tetrahydroborate; sodium azide; sulfuric acid; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate;
In
1,4-dioxane; 1,2-dimethoxyethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(84)85278-7
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 90 percent / pyridine / 1,2-dichloro-ethane / 17 h / 37 °C
2: 99 percent / pyridinium p-toluenesulfonate / 1,2-dichloro-ethane / 2 h / 60 °C
3: 87 percent / tetrabutylammonium fluoride / various solvent(s) / 1 h / 0 °C
With
pyridine; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate;
In
1,2-dichloro-ethane;
DOI:10.1016/0008-6215(84)85278-7